H3N8 avian influenza viruses (AIVs) in China caused two confirmed human infections in
2022, followed by a fatal case reported in 2023. H3N8 viruses are widespread in chicken …

Lung tissue has a certain regenerative ability and triggers repair procedures after injury.
Under controllable conditions, lung tissue can restore normal structure and function …

Pulmonary diseases like asthma, chronic obstructive pulmonary disorder, lung fibrosis, and
lung cancer pose a significant burden to global human health. Many of these complications …

Scientific progress and ethical considerations are increasingly shifting the toxicological
focus from in vivo animal models to in vitro studies utilizing physiologically relevant cell …

Background Chronic obstructive pulmonary disease (COPD) has the highest increased risk
due to household air pollution arising from biomass fuel burning. However, knowledge on …

In nasal drug product development, screening studies are vital to select promising
compounds or formulations. The Parallel Artificial Membrane Permeability Assay (PAMPA) …

Chronic respiratory diseases and infections are among the largest contributors to death
globally, many of which still have no cure, including chronic obstructive pulmonary disorder …

As part of the development of new approach methodologies (NAMs), numerous in vitro
methods are being developed to characterize the potential toxicity of inhalable xenobiotics …

Bacterial pneumonia greatly contributes to the disease burden and mortality of lower
respiratory tract infections among all age groups and risk profiles. Therefore, laboratory …

Neisseria meningitidis (Nm, the meningococcus) is considered an asymptomatic colonizer of
the upper respiratory tract and a transient member of its microbiome. It is assumed that the …