Understanding structure–function relationships of nanoadjuvants for enhanced cancer vaccine efficacy
J Tan, B Ding, B Teng, P Ma… - Advanced Functional …, 2022 - Wiley Online Library
Adjuvant, as an important part of vaccines, can observably enhance the magnitude, breadth
and durability of immune responses. Nanoadjuvants, as novel vaccine adjuvants, have …
and durability of immune responses. Nanoadjuvants, as novel vaccine adjuvants, have …
Cold to hot: rational design of a minimalist multifunctional photo-immunotherapy nanoplatform toward boosting immunotherapy capability
D Zhang, J Zhang, Q Li, A Song, Z Li… - ACS applied materials & …, 2019 - ACS Publications
The concept of integrating immunogenic cell death (ICD) with tailoring the
immunosuppressive tumor microenvironment (TME) is promising for immunotherapy …
immunosuppressive tumor microenvironment (TME) is promising for immunotherapy …
Near infrared light triggered photo/immuno-therapy toward cancers
Nanomaterials-based phototherapies, mainly including photothermal therapy (PTT),
photodynamic therapy (PDT) and photoimmunotherapy (PIT), present high efficacy, minimal …
photodynamic therapy (PDT) and photoimmunotherapy (PIT), present high efficacy, minimal …
Copper-doped nanoscale covalent organic polymer for augmented photo/chemodynamic synergistic therapy and immunotherapy
C Hu, L Cai, S Liu, Y Liu, Y Zhou… - Bioconjugate Chemistry, 2020 - ACS Publications
Due to the specific tumor microenvironment (TME) and immunosuppressive state of cancer
cells, conventional antitumor therapies face severe challenges, such as high rates of …
cells, conventional antitumor therapies face severe challenges, such as high rates of …
Size and charge dual-transformable mesoporous nanoassemblies for enhanced drug delivery and tumor penetration
A series of biological barriers in a nanoparticle-formulated drug delivery process inevitably
result in the current low delivery efficiency, limited tumor penetration and insufficient cellular …
result in the current low delivery efficiency, limited tumor penetration and insufficient cellular …
Advances in cancer theranostics using organic-inorganic hybrid nanotechnology
G Chen, Y Qian, H Zhang, A Ullah, X He, Z Zhou… - Applied Materials …, 2021 - Elsevier
A series of barriers including poor drug solubility, stability, biocompatibility, bioavailability
and pharmacokinetics, distribution to normal tissues, hemorheological flow limitations …
and pharmacokinetics, distribution to normal tissues, hemorheological flow limitations …
Phase-transition nanodroplets with immunomodulatory capabilities for potentiating mild magnetic hyperthermia to inhibit tumour proliferation and metastasis
Q Qin, Y Zhou, P Li, Y Liu, R Deng, R Tang… - Journal of …, 2023 - Springer
Background Magnetic hyperthermia (MHT)-mediated thermal ablation therapy has
promising clinical applications in destroying primary tumours. However, traditional MHT still …
promising clinical applications in destroying primary tumours. However, traditional MHT still …
[HTML][HTML] Nanoparticle delivery of immunostimulatory agents for cancer immunotherapy
Immunostimulatory agents, including adjuvants, cytokines, and monoclonal antibodies, hold
great potential for the treatment of cancer. However, their direct administration often results …
great potential for the treatment of cancer. However, their direct administration often results …
Mn2+/Fe3+/Co2+ and Tetrasulfide Bond Co‐Incorporated Dendritic Mesoporous Organosilica as Multifunctional Nanocarriers: One‐Step Synthesis and …
Enriching the application of multifunctional dendritic mesoporous organosilica (DMOS) is
still challenging in anti‐cancer research. Herein, manganese ions, iron ions, or cobalt ions …
still challenging in anti‐cancer research. Herein, manganese ions, iron ions, or cobalt ions …
Improving cancer immunotherapy outcomes using biomaterials
Immunotherapy has made great strides in improving clinical outcomes in cancer treatment.
However, few patients exhibit adequate response rates for key outcome measures and …
However, few patients exhibit adequate response rates for key outcome measures and …