The clinical use of antibiotics has led to the emergence of multidrug-resistant (MDR)
bacteria, leading to the current antibiotic resistance crisis. To address this issue, next …

Background: Post-marketing vaccine safety surveillance aims to monitor and quantify
adverse events following immunization in a population, but little is known about their …

Antibiotic overuse poses a critical global health concern, especially in low-and middle-
income countries (LMICs) where access to quality healthcare and effective regulatory …

Background Randomised controlled trials of typhoid conjugate vaccines among children in
Africa and Asia have shown high short-term efficacy. Data on the durability of protection …

(S. Typhi) caused an estimated 9.24 million cases (5.94 M, 14.1 M) of typhoid fever in 2019,
resulting in 110 000 deaths (52 800, 191 000)[1]. Over 4.8 million cases and 50 000 deaths …

Background Enteric fever is a serious public health concern. The causative agents,
Salmonella enterica serovars Typhi and Paratyphi A, are frequently antimicrobial resistant …

Typhoid fever is a serious disease that disproportionately impacts children in low-resource
settings in sub-Saharan Africa, South and Southeast Asia, and the Western Pacific. The …

Introduction Antibiotic overuse is a pressing global health concern, particularly in low-and
middle-income countries (LMICs) where there is limited access to quality healthcare and …

Typhoid fever caused by Salmonella enterica serovar Typhi (S Typhi) is a serious public
health problem in low-income and middle-income countries (LMIC). Globally about 11 …

Typhoid intestinal perforation (TIP) is a leading cause of peritonitis and indication for
emergency surgery in Africa, with reported mortality rates up to 30% in pediatric patients …