[HTML][HTML] A mini-review of the evidence for cerebrovascular changes following gender-affirming hormone replacement therapy and a call for increased focus on …

ME Wright, K Murphy - Frontiers in Human Neuroscience, 2023 - frontiersin.org
Gender-affirming hormone replacement therapy (gaHRT) is an important step for many in
the gender diverse community, associated with increased quality-of-life and lower self …

[HTML][HTML] Skeletal muscle methylome and transcriptome integration reveals profound sex differences related to muscle function and substrate metabolism

S Landen, M Jacques, D Hiam, J Alvarez-Romero… - Clinical …, 2021 - Springer
Nearly all human complex traits and diseases exhibit some degree of sex differences, with
epigenetics being one of the main contributing factors. Various tissues display sex …

Cerebral autoregulation across the menstrual cycle in eumenorrheic women

S Korad, T Mündel, JL Fan, BG Perry - Physiological Reports, 2022 - Wiley Online Library
There is emerging evidence that ovarian hormones play a significant role in the lower stroke
incidence observed in pre‐menopausal women compared with men. However, the role of …

Older females but not males exhibit increases in cerebral blood velocity, despite similar pulsatility increases after high-intensity resistance exercise

JL Marôco, AJ Rosenberg… - American Journal …, 2023 - journals.physiology.org
Sex differences in resting cerebral hemodynamics decline with aging. Given that acute
resistance exercise (RE) is a hypertensive challenge, it may reveal sex-dependent …

Age at natural menopause impacts cerebrovascular reactivity and brain structure

ME Moir, AT Corkery, KA Senese… - American Journal …, 2023 - journals.physiology.org
Menopause is associated with adverse changes in vascular health coinciding with an
increased risk of stroke and vascular cognitive impairment. However, there is significant …

Influence of sex and presence of cardiovascular risk factors on relations between cardiorespiratory fitness and cerebrovascular hemodynamics

WK Lefferts, CM Weiner, SE Mascone… - Journal of Applied …, 2022 - journals.physiology.org
Cerebral hemodynamics and pulsatility are important mechanisms of cerebrovascular and
brain health. Cardiorespiratory fitness may improve cerebrovascular pulsatility in healthy …

[HTML][HTML] Female mice display sex-specific differences in cerebrovascular function and subarachnoid haemorrhage-induced injury

DD Dinh, H Wan, D Lidington, SS Bolz - Ebiomedicine, 2024 - thelancet.com
Background In male mice, a circadian rhythm in myogenic reactivity influences the extent of
brain injury following subarachnoid haemorrhage (SAH). We hypothesized that female mice …

[HTML][HTML] Menstrual phase influences cerebrovascular responsiveness in females but may not affect sex differences

BD Skinner, SRC Weaver, SJE Lucas… - Frontiers in …, 2023 - frontiersin.org
Background and aims: Sex differences in the rate and occurrence of cerebrovascular
diseases (eg, stroke) indicate a role for female sex hormones (ie, oestrogen and …

The effects of habitual resistance exercise training on cerebrovascular responses to lower body dynamic resistance exercise: A cross‐sectional study

S Korad, T Mündel, BG Perry - Experimental Physiology, 2024 - Wiley Online Library
Dynamic resistance exercise (RE) produces sinusoidal fluctuations in blood pressure with
simultaneous fluctuations in middle cerebral artery blood velocity (MCAv). Some evidence …

[HTML][HTML] Physical Activity and the Brain: Influence of sex and presence of cardiovascular risk factors on relations between cardiorespiratory fitness and cerebrovascular …

WK Lefferts, CM Weiner, SE Mascone… - Journal of Applied …, 2022 - ncbi.nlm.nih.gov
Cerebral hemodynamics and pulsatility are important mechanisms of cerebrovascular and
brain health. Cardiorespiratory fitness may improve cerebrovascular pulsatility in healthy …