Integrins are transmembrane heterodimeric proteins sensing the cell microenvironment and
modulating numerous signalling pathways. Changes in integrin expression between normal …

Glioblastoma (GBM) is the most lethal cancer originating in the brain. Its high mortality rate
has been attributed to therapeutic resistance and rapid, diffuse invasion–both of which are …

Glioblastoma (GB) is the more frequent and malignant brain tumour. In spite of all efforts, the
median overall survival of GB patients remains approximately 15 months under therapy. The …

Originating in the brain, glioblastoma (GBM) is a highly lethal and virtually incurable cancer,
in large part because it readily develops resistance to treatments. While numerous studies …

Glioblastoma is the most common and malignant form of brain cancer. Its invasive nature
limits treatment efficacy and promotes inevitable recurrence. Previous in vitro studies …

Integrins are the main cell surface receptors and execute multifaceted functions such as the
bidirectional transmission of signals (ie, inside-out and outside-in) and provide …

New molecular insight reveals novel points of attack for targeted cancer therapy. The recent
advances in cancer genomics and novel insight into the complex biology of cancer make the …

Gliomas are primary malignant brain tumors. These tumors seem to be more and more
frequent, not only because of a true increase in their incidence, but also due to the increase …

Abstract Interferon γ (IFN-γ), a multifunctional cytokine, was upregulated in the resected
gastric cancer tissue. However, whether IFN-γ is involved in the regulation of gastric cancer …

Glioblastoma (GBM) is the most common, yet most lethal, central nervous system cancer. In
recent years, many studies have focused on how the extracellular matrix (ECM) of the …