Idiopathic pulmonary fibrosis (IPF) is a chronic progressive fibrotic interstitial pneumonia
with unknown causes. The incidence rate increases year by year and the prognosis is poor …

Fibrosis is the extensive deposition of fibrous connective tissue, and it is characterized by
the accumulation of collagen and other extracellular matrix (ECM) components. Fibrosis is …

Primary tumors are drivers of pre-metastatic niche formation, but the coordination by the
secondary organ toward metastatic dissemination is underappreciated. Here, by single-cell …

Some patients hospitalized with acute COVID-19 suffer respiratory symptoms that persist for
many months. We delineated the immune-proteomic landscape in the airways and …

A subset of individuals who recover from coronavirus disease 2019 (COVID-19) develop
post-acute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

Interstitial lung diseases (ILDs), which can arise from a broad spectrum of distinct
aetiologies, can manifest as a pulmonary complication of an underlying autoimmune and …

Interleukins, a group of cytokines participating in inflammation and immune response, are
proved to be involved in the formation and development of pulmonary fibrosis. In this article …

The anti-inflammatory and immunomodulatory abilities of oral selective phosphodiesterase
4 (PDE4) inhibitors enabled the approval of roflumilast and apremilast for use in chronic …

Pulmonary fibrosis (PF) is a serious and progressive lung disease which is possibly life-
threatening. It causes lung scarring and affects lung functions including epithelial cell injury …

Pulmonary fibrosis is a chronic and fatal lung disease that significantly impacts the aging
population globally. To date, anti-fibrotic, immunosuppressive, and other adjunct therapy …