Lennox-Gastaut syndrome (LGS) is a childhood epileptic encephalopathy characterized by
an electroclinical triad of generalized slow spike wave (SSW) activity in the EEG, multiple …

One of the most challenging areas in nosology is in the field of severe generalized epilepsy
of early childhood. This is certainly true in the case of Lennox‐Gastaut syndrome (LGS), an …

Lennox‐Gastaut syndrome (LGS) is a rare epileptic encephalopathy with a peak age of
onset of 3–5 years of age. Reported prevalence rates for LGS vary widely from 1–10% of all …

Epileptic encephalopathies are a group of diseases in which epileptic activity itself
contributes to severe cognitive and behavioral impairments above and beyond what might …

Idiopathic generalized epilepsy (IGE) is a common type of epilepsy and despite an increase
in the number of available anti-seizure medications, approximately 20–30% of people with …

The voltage-gated sodium channels are fundamental units that evoke the action potential in
excitable cells such as neurons. These channels are integral membrane proteins typically …

Lennox–Gastaut Syndrome (LGS) is a category of severe, disabling epilepsy, characterized
by frequent, treatment-resistant seizures, and cognitive impairment. Electroencephalography …

Cognitive impairment associated with childhood-onset epilepsy is an important
consequence in the developing brain owing to its negative effects on neurodevelopmental …

Lennox–Gastaut syndrome (LGS) is a severe age-dependent epileptic encephalopathy
usually with onset between 1 and 8 years of age. Functional neuroimaging studies recently …

Background. The relationship between sleep and epilepsy has been long ago studied, and
several excellent reviews are available. However, recent development in sleep research, the …