Colorectal cancer (CRC) is one of the most common cancers, with an annual incidence of~
135,000 in the US, associated with~ 50,000 deaths. Autosomal dominant polycystic kidney …

Type 2 diabetes mellitus (T2DM) is a progressive disease, which affects colorectal cancer
(CRC) survival. However, data on the relationship between CRC survival and T2DM …

The disorders of gastrointestinal (GI) tract including intestine and colon are common in the
patients with diabetes mellitus (DM). DM induced intestinal and colonic structural and …

Background: Metformin has been reported to inhibit the growth of various types of cancers,
including breast cancer. Yet the mechanisms underlying the anticancer effects of metformin …

Colorectal cancer (CRC) is a major health problem worldwide, with an estimated 1.9 million
new cases and 915,880 deaths in 2020 alone. The etiology of CRC is complex and involves …

Introduction Recent statistics have reported colorectal cancer (CRC) as the second leading
cause of cancer-associated deaths in the world. Early diagnosis of CRC may help to reduce …

Background and Aims Postpolypectomy risk stratification for subsequent metachronous
advanced neoplasia (MAN) is imprecise and does not account for colonoscopist adenoma …

Purpose Aldo-keto reductases (including AKR1B1 and AKR1B10) constitute a family of
oxidoreductases that have been implicated in the pathophysiology of diabetes and cancer …

Asparagine (Asn) and enzymes that catalyze the metabolism of Asn have been linked to the
regulation and propagation of colorectal cancer (CRC). Increased Asn and asparagine …

Abstract Type 2 diabetes (T2D) is a major cause of complications and death in many
countries. The possible causal relation between T2D and cancer has been the aim of many …