Recent progresses in exosome-based systems for targeted drug delivery to the brain

S Bashyal, C Thapa, S Lee - Journal of Controlled Release, 2022 - Elsevier
Despite the multiple ongoing and novel initiatives for developing brain-targeted drug
delivery systems, insurmountable obstacles remain. A perfect drug delivery device that can …

[HTML][HTML] The role of the tumor microenvironment and treatment strategies in colorectal cancer

Y Chen, X Zheng, C Wu - Frontiers in immunology, 2021 - frontiersin.org
Colorectal cancer (CRC) has the second highest mortality rate among all cancers
worldwide. Surgery, chemotherapy, radiotherapy, molecular targeting and other treatment …

Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin

RE Veerman, L Teeuwen, P Czarnewski… - Journal of …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) are increasingly tested as therapeutic vehicles and biomarkers,
but still EV subtypes are not fully characterised. To isolate EVs with few co‐isolated entities …

Carbon nanomaterials-based electrochemical aptasensor for point-of-care diagnostics of cancer biomarkers

A Parihar, NK Choudhary, P Sharma, R Khan - Materials Today Chemistry, 2023 - Elsevier
Nanomaterials have been extensively utilized in the fabrication of a wide range of
biosensors for the diagnostics of cancerous and non-cancerous diseases. Owing to their …

[HTML][HTML] Exosomes-based nanomedicine for neurodegenerative diseases: current insights and future challenges

A Cano, Á Muñoz-Morales, E Sánchez-López… - Pharmaceutics, 2023 - mdpi.com
Neurodegenerative diseases constitute a group of pathologies whose etiology remains
unknown in many cases, and there are no treatments that stop the progression of such …

Overview of extracellular vesicle characterization techniques and introduction to combined reflectance and fluorescence confocal microscopy to distinguish …

C Bağcı, M Sever-Bahcekapili, N Belder… - …, 2022 - spiedigitallibrary.org
Extracellular vesicles (EVs) are nanoparticles (30 to 1000 nm in diameter) surrounded by a
lipid-bilayer which carry bioactive molecules between local and distal cells and participate in …

Diagnostic and therapeutic potential of extracellular vesicles

SP Kodam, M Ullah - Technology in Cancer Research & …, 2021 - journals.sagepub.com
Extracellular vesicles (EVs) are naturally phospholipid enclosed nanovesicles released by
many cells in the body. They are stable in circulation, have low immunogenicity, and act as …

Exosomics in oral cancer diagnosis, prognosis, and therapeutics–An emergent and imperative non-invasive natural nanoparticle-based approach

A Bano, R Vats, P Yadav, R Bhardwaj - Critical Reviews in Oncology …, 2022 - Elsevier
Exosomes-the natural nanoparticles belonging to heterogeneous vesicles are released via
nearly all sorts of cells, including tumour cells, to oprate intercellular communication …

Recent developments in biosensing methods for extracellular vesicle protein characterization

J Suthar, M Taub, RP Carney… - Wiley …, 2023 - Wiley Online Library
Research into extracellular vesicles (EVs) has grown significantly over the last few decades
with EVs being widely regarded as a source of biomarkers for human health and disease …

[HTML][HTML] Extracellular vesicles from human cerebrospinal fluid are effectively separated by sepharose CL-6B—Comparison of four gravity-flow size exclusion …

V Krušić Alić, M Malenica, M Biberić, S Zrna, L Valenčić… - Biomedicines, 2022 - mdpi.com
Extracellular vesicles (EVs) are a versatile group of cell-secreted membranous
nanoparticles present in body fluids. They have an exceptional diagnostic potential due to …