[HTML][HTML] An Overview of Helicobacter pylori Survival Tactics in the Hostile Human Stomach Environment

YY Cheok, CYQ Lee, HC Cheong, J Vadivelu, CY Looi… - Microorganisms, 2021 - mdpi.com
Helicobacter pylori is well established as a causative agent for gastritis, peptic ulcer, and
gastric cancer. Armed with various inimitable virulence factors, this Gram-negative bacterium …

Discussion on the common controversies of Helicobacter pylori infection

H Yang, Y Mou, B Hu - Helicobacter, 2023 - Wiley Online Library
Background Helicobacter pylori (H. pylori) can persistently colonize on the gastric mucosa
after infection and cause gastritis, atrophy, metaplasia, and even gastric cancer (GC) …

Combating drug-resistant helicobacter pylori infection with zinc peroxide-based nanoparticles: a ROS reservoir via photochemical reaction

KI Wong, S Wang, M Li, G Zhao, C Wang, L Wu… - Chemical Engineering …, 2024 - Elsevier
Addressing the challenge of treating Helicobacter pylori infection while ensuring the safety
of other microorganisms, such as intestinal microbiota, is of paramount importance. In this …

[HTML][HTML] A small-molecular inhibitor against Proteus mirabilis urease to treat catheter-associated urinary tract infections

S Milo, RA Heylen, J Glancy, GT Williams… - Scientific reports, 2021 - nature.com
Infection and blockage of indwelling urinary catheters is significant owing to its high
incidence rate and severe medical consequences. Bacterial enzymes are employed as …

Isoindolin-1-ones fused to barbiturates: from design and molecular docking to synthesis and urease inhibitory evaluation

H Kazemzadeh, E Hamidian, FS Hosseini, M Abdi… - ACS …, 2022 - ACS Publications
Helicobacter pylori-induced ulcers and gastric cancer have been one of the main obstacles
that the human community has ever struggled with, especially in recent decades. Several …

Sanguinarine, a major alkaloid from Zanthoxylum nitidum (Roxb.) DC., inhibits urease of Helicobacter pylori and jack bean: Susceptibility and mechanism

Q Lu, Z Zhang, Y Xu, Y Chen, C Li - Journal of Ethnopharmacology, 2022 - Elsevier
Abstract Ethnopharmacological relevance Zanthoxylum nitidum (Roxb.) DC.(Z. nitidum) is a
traditional Chinese medicine and mainly adopted to treat gastric ulcer, gastritis and stomach …

The Role of Adhesion in Helicobacter pylori Persistent Colonization

H Yang, L Wang, M Zhang, B Hu - Current Microbiology, 2023 - Springer
Helicobacter pylori (H. pylori) has coevolved with its human host for more than 100 000
years. It can safely colonize around the epithelium of gastric glands via their specific …

[HTML][HTML] Gossypol from Gossypium spp. Inhibits Helicobacter pylori Clinical Strains and Urease Enzyme Activity: Bioactivity and Safety Assessments

M Šudomová, STS Hassan - Scientia Pharmaceutica, 2022 - mdpi.com
This study investigates the inhibitory activities of gossypol, a natural polyphenolic compound
from Gossypium spp., against Helicobacter pylori (HP) clinical strains and a urease enzyme …

[HTML][HTML] Targeting the protein tunnels of the urease accessory complex: a theoretical investigation

M Masetti, F Falchi, D Gioia, M Recanatini, S Ciurli… - Molecules, 2020 - mdpi.com
Urease is a nickel-containing enzyme that is essential for the survival of several and often
deadly pathogenic bacterial strains, including Helicobacter pylori. Notwithstanding several …

Pangenome Analysis of Helicobacter pylori Isolates from Selected Areas of Africa Indicated Diverse Antibiotic Resistance and Virulence Genes

B Yakubu, EM Appiah, AF Adu - International Journal of …, 2024 - Wiley Online Library
The challenge facing Helicobacter pylori (H. pylori) infection management in some parts of
Africa is the evolution of drug‐resistant species, the lack of gold standard in diagnostic …