Biofilm-associated infections have emerged as a significant public health challenge due to
their persistent nature and increased resistance to conventional treatment methods. The …

Nanotechnology brings hope for targeted drug delivery. However, most current drug delivery
systems used passive delivery strategies with limited therapeutic efficiency. Over the past …

It is an effective method of eradicating biofilm infection and promoting wound healing by
exopolysaccharides (EPS) degradation and penetration of antimicrobial agents into biofilms …

d-Amino acids are signals for biofilm disassembly. However, unexpected metabolic
pathways severely attenuate the utilization of d-amino acids in biofilm disassembly, resulting …

Recent efforts have focused on developing improved drug delivery systems with enhanced
therapeutic efficacy and minimal side effects. Micelles, self-assembled from amphiphilic …

Chronic inflammatory conditions are among the most prevalent diseases worldwide. Several
debilitating diseases such as atherosclerosis, inflammatory bowel disease, rheumatoid …

Combating bacterial biofilm poses a significant challenge because of the dense extracellular
polymeric substance (EPS) barrier and inherent drug tolerance. Herein, the designed core …

Microbial biofilms are complex three‐dimensional structures where sessile microbes are
embedded in a polymeric extracellular matrix. Their resistance toward the host immune …

Bacterial infections threaten public health, and novel therapeutic strategies critically demand
to be explored. Herein, poly (amino acid)(PAA)-based drug delivery nanoparticles (NPs) …

The effective transportation of antibiotics to bacteria embedded within a biofilm consisting of
a dense matrix of extracellular polymeric substances is still a challenge in the treatment of …