Advances in nanotechnology for biofilm inhibition
Biofilm-associated infections have emerged as a significant public health challenge due to
their persistent nature and increased resistance to conventional treatment methods. The …
their persistent nature and increased resistance to conventional treatment methods. The …
Light-driven micro/nanomotors in biomedical applications
X Zeng, M Yang, H Liu, Z Zhang, Y Hu, J Shi, ZH Wang - Nanoscale, 2023 - pubs.rsc.org
Nanotechnology brings hope for targeted drug delivery. However, most current drug delivery
systems used passive delivery strategies with limited therapeutic efficiency. Over the past …
systems used passive delivery strategies with limited therapeutic efficiency. Over the past …
Enzymolysis and photothermal-mediated synergistic antimicrobial nanoplatform with programmed EPS degradation and biofilm penetration capabilities for eradication …
D Qiu, C Zheng, Y Zeng, L Wu, C Huang, Y Ran… - Chemical Engineering …, 2023 - Elsevier
It is an effective method of eradicating biofilm infection and promoting wound healing by
exopolysaccharides (EPS) degradation and penetration of antimicrobial agents into biofilms …
exopolysaccharides (EPS) degradation and penetration of antimicrobial agents into biofilms …
Poly(d-amino acid) Nanoparticles Target Staphylococcal Growth and Biofilm Disassembly by Interfering with Peptidoglycan Synthesis
W Feng, M Chittò, W Xie, Q Ren, F Liu, X Kang… - ACS …, 2024 - ACS Publications
d-Amino acids are signals for biofilm disassembly. However, unexpected metabolic
pathways severely attenuate the utilization of d-amino acids in biofilm disassembly, resulting …
pathways severely attenuate the utilization of d-amino acids in biofilm disassembly, resulting …
Current paradigms in employing self-assembled structures: Drug delivery implications with improved therapeutic potential
Recent efforts have focused on developing improved drug delivery systems with enhanced
therapeutic efficacy and minimal side effects. Micelles, self-assembled from amphiphilic …
therapeutic efficacy and minimal side effects. Micelles, self-assembled from amphiphilic …
Iron oxide nanoparticles for treatment and diagnosis of chronic inflammatory diseases: A systematic review
Chronic inflammatory conditions are among the most prevalent diseases worldwide. Several
debilitating diseases such as atherosclerosis, inflammatory bowel disease, rheumatoid …
debilitating diseases such as atherosclerosis, inflammatory bowel disease, rheumatoid …
Programmed degradable core-shell nanoparticles eradicate mature biofilm via precise in-situ phototherapy
F Bu, M Liu, W Zhao, F Liu, W Xie, G Li, X Wang - Nano Today, 2024 - Elsevier
Combating bacterial biofilm poses a significant challenge because of the dense extracellular
polymeric substance (EPS) barrier and inherent drug tolerance. Herein, the designed core …
polymeric substance (EPS) barrier and inherent drug tolerance. Herein, the designed core …
Nanomedicine against biofilm infections: A roadmap of challenges and limitations
N Blanco‐Cabra, J Alcàcer‐Almansa… - Wiley …, 2024 - Wiley Online Library
Microbial biofilms are complex three‐dimensional structures where sessile microbes are
embedded in a polymeric extracellular matrix. Their resistance toward the host immune …
embedded in a polymeric extracellular matrix. Their resistance toward the host immune …
Poly (amino acid)-based drug delivery nanoparticles eliminate Methicillin resistant Staphylococcus aureus via tunable release of antibiotic
H Li, L Yang, W Feng, W Liu, M Wang, F Liu, G Li… - Colloids and Surfaces B …, 2024 - Elsevier
Bacterial infections threaten public health, and novel therapeutic strategies critically demand
to be explored. Herein, poly (amino acid)(PAA)-based drug delivery nanoparticles (NPs) …
to be explored. Herein, poly (amino acid)(PAA)-based drug delivery nanoparticles (NPs) …
Quaternary ammonium-tethered hyperbranched polyurea nanoassembly synergized with antibiotics for enhanced antimicrobial efficacy
Y Feng, J Bian, G Yu, P Zhao, J Yue - Biomaterials Science, 2024 - pubs.rsc.org
The effective transportation of antibiotics to bacteria embedded within a biofilm consisting of
a dense matrix of extracellular polymeric substances is still a challenge in the treatment of …
a dense matrix of extracellular polymeric substances is still a challenge in the treatment of …