[HTML][HTML] The interplay between prolactin and cardiovascular disease

A Glezer, MR Santana, MD Bronstein… - Frontiers in …, 2023 - frontiersin.org
Hyperprolactinemia can be caused by several conditions and its effects on the hypothalamic-
pituitary-gonadal axis are understood in more detail. Nevertheless, in recent decades, other …

[HTML][HTML] Striatal dopamine D2-like receptors availability in obesity and its modulation by bariatric surgery: a systematic review and meta-analysis

G Ribeiro, A Maia, G Cotovio, FPM Oliveira… - Scientific Reports, 2023 - nature.com
There is significant evidence linking a 'reward deficiency syndrome'(RDS), comprising
decreased availability of striatal dopamine D2-like receptors (DD2lR) and addiction-like …

Brain dopamine receptor system is not altered in obesity: Bayesian and frequentist meta‐analyses

K Pak, L Nummenmaa - Human brain mapping, 2023 - Wiley Online Library
Feeding induces dopamine release in the striatum, and a dysfunction of the dopaminergic
reward system can lead to overeating, and obesity. Studies have reported inconsistent …

The 'Behavioral Balance Model': A new perspective on the aetiology and therapy of obesity

B Schultes, B Ernst, M Hallschmid… - Diabetes, Obesity …, 2023 - Wiley Online Library
Obesity is a debilitating disease of global proportions that necessitates refined, concept‐
driven therapeutic approaches. Policy makers, the public and even health care …

Paediatric obesity and metabolic syndrome associations with cognition and the brain in youth: Current evidence and future directions

JR Sadler, G Thapaliya, K Ranganath… - Pediatric …, 2023 - Wiley Online Library
Obesity and components of the metabolic syndrome (MetS) are associated with differences
in brain structure and function and in general and food‐related cognition in adults. Here, we …

Working memory gating in obesity: Insights from a case-control fMRI study

N Herzog, H Hartmann, LK Janssen, M Waltmann… - Appetite, 2024 - Elsevier
Computational models and neurophysiological data propose that a 'gating mechanism'
coordinates distractor-resistant maintenance and flexible updating of working memory …

[HTML][HTML] Self-reported intake of high-fat and high-sugar diet is not associated with cognitive stability and flexibility in healthy men

H Hartmann, LK Janssen, N Herzog, F Morys… - Appetite, 2023 - Elsevier
Animal studies indicate that a high-fat/high-sugar diet (HFS) can change dopamine signal
transmission in the brain, which could promote maladaptive behavior and decision-making …

[HTML][HTML] Distinct adaptations of endocrine and cognitive functions may contribute to high variability in long-term weight loss outcome after bariatric surgery

M Lammert, E Medawar, H Hartmann, L Grasser… - Physiology & …, 2023 - Elsevier
Background: Bariatric surgery has been widely recognized as the most efficient long-term
treatment method in severe obesity, yet therapy success shows considerable interindividual …

[HTML][HTML] Striatal dopamine tone is positively associated with body mass index in humans as determined by PET using dual dopamine type-2 receptor antagonist …

VL Darcey, J Guo, M Chi, ST Chung, AB Courville… - medRxiv, 2023 - ncbi.nlm.nih.gov
The relationship between adiposity and dopamine type-2 receptor binding potential (D2BP)
in the human brain has been repeatedly studied for> 20 years with highly discrepant results …

Obesity‐induced tissue alterations resist weight loss: A mechanistic review

L Della Guardia, AC Shin - Diabetes, Obesity and Metabolism, 2024 - Wiley Online Library
Interventions aimed at weight control often have limited effectiveness in combating obesity.
This review explores how obesity‐induced dysfunction in white (WAT) and brown adipose …