Recent advances in codelivery of curcumin and siRNA as anticancer therapeutics

M Sanati, AR Afshari, P Kesharwani… - European Polymer …, 2023 - Elsevier
Addressing the need for effective cancer chemotherapy with low adverse effects has been
partially possible through innovative therapeutic approaches combining chemotherapeutics …

The intracellular fate and transport mechanism of shape, size and rigidity varied nanocarriers for understanding their oral delivery efficiency

X Li, SM Jafari, F Zhou, H Hong, X Jia, X Mei, G Hou… - Biomaterials, 2023 - Elsevier
Nanocarriers have become an effective strategy to overcome epithelial absorption barriers.
During the absorption process, the endocytosis mechanisms, cell internalization pathways …

Bioactive compounds: Application of albumin nanocarriers as delivery systems

FF Visentini, AA Perez, LG Santiago - Critical reviews in food …, 2023 - Taylor & Francis
Enriched products with bioactive compounds (BCs) show the capacity to produce a wide
range of possible health effects. Most BCs are essentially hydrophobic and sensitive to …

The stability and bioavailability of curcumin loaded α-lactalbumin nanocarriers formulated in functional dairy drink

Q Wang, W Yu, Z Li, B Liu, Y Hu, S Chen, R de Vries… - Food …, 2022 - Elsevier
There is a high demand for the development of functional foods formulated with health-
promoting carotenoids. Curcumin (Cur) is one of the most promising carotenoids, but its …

Experimental and theoretical explorations of nanocarriers' multistep delivery performance for rational design and anticancer prediction

W Bao, F Tian, C Lyu, B Liu, B Li, L Zhang, X Liu… - Science …, 2021 - science.org
The poor understanding of the complex multistep process taken by nanocarriers during the
delivery process limits the delivery efficiencies and further hinders the translation of these …

iRGD-grafted N-trimethyl chitosan-coated protein nanotubes enhanced the anticancer efficacy of curcumin and melittin

G Hou, Y Li, Q Wang, H Zhang, S Liang, B Liu… - International Journal of …, 2022 - Elsevier
Abstract Curcumin (Cur) and Melittin (Mel) are two natural extracts that have been shown
anti-tumor effects. However, their applications are limited due to poor oral bioavailability and …

On demand regulation of blood glucose level by biocompatible oxidized starch-Con A nanogels for glucose-responsive release of exenatide

J Bai, H Zhang, Z Yang, P Li, B Liu, D Li, S Liang… - Journal of Controlled …, 2022 - Elsevier
Diabetes mellitus is a long-term chronic disease characterized by abnormal high level blood
glucose (BG). An artificial closed-loop system that mimics pancreatic β-cells and releases …

Optimization extraction and purification of biological activity curcumin from Curcuma longa L by high‐performance counter‐current chromatography

Y Pan, R Ju, X Cao, H Pei, T Zheng… - Journal of separation …, 2020 - Wiley Online Library
The extraction condition of curcumin from Curcuma longa L was optimized through four
factors and three levels orthogonal experiment based on the results of single factor tests …

Natural products: Potential lead compounds for the treatment of endometriosis

N Machairiotis, S Vasilakaki, P Kouroutou - European Journal of Obstetrics …, 2020 - Elsevier
Objective Medical plants have been used for centuries for the treatment of various disorders
in humans and animals. The therapeutic properties of herbs and plants have been …

Nanospheres for curcumin delivery as a precision nanomedicine in cancer therapy

M Mahjoubin-Tehran, S Rezaei… - Journal of …, 2024 - Taylor & Francis
Cancer is ranked among the top causes of mortality throughout the world. Conventional
therapies are associated with toxicity and undesirable side effects, rendering them …