THE PATHOGENESIS OF HELICOBACTER PYLORI–INDUCED GASTRO-DUODENAL DISEASES

JC Atherton - Annu. Rev. Pathol. Mech. Dis., 2006 - annualreviews.org
Helicobacter pylori is the main cause of peptic ulceration, distal gastric adenocarcinoma,
and gastric lymphoma. Only 15% of those colonized develop disease, and pathogenesis …

Gastrin—active participant or bystander in gastric carcinogenesis?

SA Watson, AM Grabowska, M El-Zaatari… - Nature Reviews …, 2006 - nature.com
Gastrin is a pro-proliferative, anti-apoptotic hormone with a central role in acid secretion in
the gastric mucosa and a long-standing association with malignant progression in …

Mechanism for gastric cancer development by Helicobacter pylori infection

T Chiba, H Marusawa, H Seno… - … of gastroenterology and …, 2008 - Wiley Online Library
Helicobacter pylori (H. pylori) infection plays a crucial role in the development of gastric
cancer. There are two major pathways for the development of gastric cancer by H. pylori …

[图书][B] Animal lectins: form, function and clinical applications

GS Gupta - 2012 - books.google.com
Animal Lectins: Form, Function and Clinical Applications presents up-to-date knowledge of
animal lectins. Detailed descriptions on biological activities, tissue and/or subcellular …

[HTML][HTML] Involvement of the IL-22/REG Iα axis in ulcerative colitis

A Sekikawa, H Fukui, K Suzuki, T Karibe, S Fujii… - Laboratory …, 2010 - Elsevier
Abstract The Regenerating gene (REG) Iα protein, a trophic and/or anti-apoptotic factor, is
important in the pathophysiology of gastrointestinal inflammation. Interleukin (IL)-22 is a …

The potential role of REG family proteins in inflammatory and inflammation-associated diseases of the gastrointestinal tract

C Sun, X Wang, Y Hui, H Fukui, B Wang… - International Journal of …, 2021 - mdpi.com
Regenerating gene (REG) family proteins serve as multifunctional secretory molecules with
trophic, antiapoptotic, anti-inflammatory, antimicrobial and probably immuno-regulatory …

REG Iα protein may function as a trophic and/or anti-apoptotic factor in the development of gastric cancer

A Sekikawa, H Fukui, S Fujii, J Takeda, A Nanakin… - Gastroenterology, 2005 - Elsevier
Background & Aims: Although a significant amount of regenerating gene (REG) Iα protein is
present not only in normal gastric mucosa but also in gastric cancer tissues, its …

REG Iα protein mediates an anti-apoptotic effect of STAT3 signaling in gastric cancer cells

A Sekikawa, H Fukui, S Fujii, K Ichikawa… - …, 2008 - academic.oup.com
Signal transducer and activator of transcription 3 (STAT3) signaling plays roles in
inflammation-associated carcinogenesis. Regenerating gene (REG) Iα protein, an …

Possible role of REG Iα protein in ulcerative colitis and colitic cancer

A Sekikawa, H Fukui, S Fujii, A Nanakin, N Kanda… - Gut, 2005 - gut.bmj.com
Background and aims: Although regenerating gene (REG) Iα protein may be involved in the
inflammation and carcinogenesis in the gastrointestinal tract, its pathophysiological role in …

Expression of REG family genes in human inflammatory bowel diseases and its regulation

C Tsuchida, S Sakuramoto-Tsuchida, M Taked… - … and biophysics reports, 2017 - Elsevier
The pathophysiology of inflammatory bowel disease (IBD) reflects a balance between
mucosal injury and reparative mechanisms. Some regenerating gene (Reg) family members …