Cell-free fetal DNA testing and its correlation with prenatal indications
J Wang, Y Lyu, B Qiao, Y Li, Y Zhang… - BMC Pregnancy and …, 2021 - Springer
Background The prenatal test of cell-free fetal DNA (cffDNA) is also known as noninvasive
prenatal testing (NIPT) with high sensitivity and specificity. This study is to evaluate the …
prenatal testing (NIPT) with high sensitivity and specificity. This study is to evaluate the …
Retrospective details of false-positive and false-negative results in non-invasive prenatal testing for fetal trisomies 21, 18 and 13
N Suzumori, A Sekizawa, E Takeda, O Samura… - European Journal of …, 2021 - Elsevier
Objective Maternal characteristics and neonatal outcomes associated with cell-free DNA
(cfDNA) results were analysed retrospectively to assess the details of false-positive and …
(cfDNA) results were analysed retrospectively to assess the details of false-positive and …
Evaluation of the clinical utility of extended non-invasive prenatal testing in the detection of chromosomal aneuploidy and microdeletion/microduplication
W Tian, Y Yuan, E Yuan, L Zhang, L Liu, Y Li… - European Journal of …, 2023 - Springer
Background With the development of whole-genome sequencing technology, non-invasive
prenatal testing (NIPT) has been applied gradually to screen chromosomal microdeletions …
prenatal testing (NIPT) has been applied gradually to screen chromosomal microdeletions …
Evaluation of the Z‐score accuracy of noninvasive prenatal testing for fetal trisomies 13, 18 and 21 at a single center
W Junhui, L Ru, Y Qiuxia, W Dan, S Xiuhong… - Prenatal …, 2021 - Wiley Online Library
Objective To assess the correlation between Z‐scores of positive noninvasive prenatal
testing (NIPT) results and the positive predictive value (PPV) of NIPT. Methods Pregnancies …
testing (NIPT) results and the positive predictive value (PPV) of NIPT. Methods Pregnancies …
Noninvasive prenatal screening in Southeast China: clinical application and accuracy evaluation
L Wen, J Gao, L Huang, D Li… - Expert Review of Molecular …, 2022 - Taylor & Francis
Objective To assess the clinical performance of noninvasive prenatal screening (NIPS) for
both common trisomy and sex chromosome aneuploidy (SCA). Methods We recruited …
both common trisomy and sex chromosome aneuploidy (SCA). Methods We recruited …
Noninvasive prenatal screening based on second-trimester ultrasonographic soft markers in low-risk pregnant women
Y Liu, X Jing, L Xing, S Liu, J Liu, J Cheng… - Frontiers in …, 2021 - frontiersin.org
Background: We aimed to assess the clinical application of noninvasive prenatal screening
(NIPS) based on second-trimester ultrasonographic soft markers (USMs) in low-risk …
(NIPS) based on second-trimester ultrasonographic soft markers (USMs) in low-risk …
Comparison of the performance of NIPT and NIPT‐plus for fetal chromosomal aneuploidy and high Z‐score increases the positive predictive value
S Liu, Y Xu, Q Chang, B Jia, F Li - International Journal of …, 2024 - Wiley Online Library
Objective To evaluate non‐invasive prenatal testing (NIPT) and expanded non‐invasive
prenatal testing (NIPT‐plus) for detecting aneuploidies at different sequencing depths and …
prenatal testing (NIPT‐plus) for detecting aneuploidies at different sequencing depths and …
Combining Z-score and maternal copy number variation analysis increases the positive rate and accuracy in non-invasive prenatal testing
L Chen, L Wang, Z Hu, Y Tao, W Song, Y An… - Frontiers in …, 2022 - frontiersin.org
Objective: To evaluate positive rate and accuracy of non-invasive prenatal testing (NIPT)
combining Z-score and maternal copy number variation (CNV) analysis. To assess the …
combining Z-score and maternal copy number variation (CNV) analysis. To assess the …
A high Z-score might increase the positive predictive value of cell-free noninvasive prenatal testing for singleton-pregnant women
L Ma, Y Li, L Li, H Wu, Y Liu, X Yang… - The Journal of Maternal …, 2023 - Taylor & Francis
Objective To explore the positive predictive value (PPV) in noninvasive prenatal testing
(NIPT)-positive cases and analyze the effect of the Z-score intervals on PPV performance …
(NIPT)-positive cases and analyze the effect of the Z-score intervals on PPV performance …
The optimal cutoff value of Z-scores enhances the judgment accuracy of noninvasive prenatal screening
L Zhou, B Zhang, J Liu, Y Shi, J Wang, B Yu - Frontiers in Genetics, 2021 - frontiersin.org
Objective To evaluate the accuracy of Z-scores of noninvasive prenatal screening (NIPS) in
predicting 21, 18 trisomy, and X chromosome aneuploidy. Methods A total of 39,310 …
predicting 21, 18 trisomy, and X chromosome aneuploidy. Methods A total of 39,310 …