This review gives a comprehensive overview of cancer development and links it to the
current understanding of tumorigenesis and malignant progression in colorectal cancer. The …

Several epidemiological, clinical and experimental studies established nonsteroidal anti-
inflammatory drugs (NSAIDs) as promising cancer chemopreventive agents. Long-term use …

Downhill running is associated with fiber damage, inflammation, delayed-onset muscle
soreness, and various functional deficits. Curcumin, a constituent of the Indian spice turmeric …

Purpose: Patients with pancreatic ductal adenocarcinoma usually present with advanced-
stage disease and a dismal prognosis. One effective strategy likely to improve the morbidity …

Abstract Purpose: Macrophage inhibitory cytokine-1 (MIC-1) is a divergent member of the
tumor growth factor β (TGF-β) superfamily. Several observations suggest that it plays a role …

Cyclooxygenasel (COX1) and COX2 mediate the rate‐limiting step in arachidonic acid me¬
tabolism. Expression of COX2 mRNA and protein is often enhanced in various human cell …

Background: Angiogenesis, the growth of new blood vessels, is a critical homeostatic
mechanism which regulates vascular populations in response to physiological requirements …

The use of herbs for medical benefit has played an important role in nearly every culture on
earth. Herbal medicine was practiced by ancient cultures in Asia, Africa, Europe and the …

The inducible isoforms of nitric oxide synthase (iNOS) and cyclooxygenase (COX-2) are
overexpressed in colonic tumors of humans, as well as in colon tumors that develop in rats …

There is an increasing demand for biomarkers in colon cancer for risk assessment, early
detection, prognosis, and surrogate end points. A number of biomarkers have been …