Composition, structure and mechanical properties define performance of pulmonary surfactant membranes and films
E Parra, J Pérez-Gil - Chemistry and physics of lipids, 2015 - Elsevier
The respiratory surface in the mammalian lung is stabilized by pulmonary surfactant, a
membrane-based system composed of multiple lipids and specific proteins, the primary …
membrane-based system composed of multiple lipids and specific proteins, the primary …
[HTML][HTML] Current perspectives in pulmonary surfactant—inhibition, enhancement and evaluation
Pulmonary surfactant (PS) is a complicated mixture of approximately 90% lipids and 10%
proteins. It plays an important role in maintaining normal respiratory mechanics by reducing …
proteins. It plays an important role in maintaining normal respiratory mechanics by reducing …
Protein–lipid interactions and surface activity in the pulmonary surfactant system
AG Serrano, J Pérez-Gil - Chemistry and physics of lipids, 2006 - Elsevier
Pulmonary surfactant is a lipid–protein complex, synthesized and secreted by the respiratory
epithelium of lungs to the alveolar spaces, whose main function is to reduce the surface …
epithelium of lungs to the alveolar spaces, whose main function is to reduce the surface …
[HTML][HTML] Cholesterol rules: direct observation of the coexistence of two fluid phases in native pulmonary surfactant membranes at physiological temperatures
Pulmonary surfactant, the lipid-protein material that stabilizes the respiratory surface of the
lungs, contains approximately equimolar amounts of saturated and unsaturated …
lungs, contains approximately equimolar amounts of saturated and unsaturated …
Interfacial properties of pulmonary surfactant layers
R Wüstneck, J Perez-Gil, N Wüstneck, A Cruz… - Advances in colloid and …, 2005 - Elsevier
The composition of the pulmonary surfactant and the border conditions of normal human
breathing are relevant to characterize the interfacial behavior of pulmonary layers. Based on …
breathing are relevant to characterize the interfacial behavior of pulmonary layers. Based on …
Biochemical and pharmacological differences between preparations of exogenous natural surfactant used to treat Respiratory Distress Syndrome: role of the different …
O Blanco, J Pérez-Gil - European journal of pharmacology, 2007 - Elsevier
The pharmaceutical application of exogenous natural pulmonary surfactant preparations
has shown its efficiency in the therapeutical treatment of infants with Respiratory Distress …
has shown its efficiency in the therapeutical treatment of infants with Respiratory Distress …
[HTML][HTML] Inactivation of pulmonary surfactant due to serum-inhibited adsorption and reversal by hydrophilic polymers: experimental
HW Taeusch, JB De La Serna, J Perez-Gil, C Alonso… - Biophysical journal, 2005 - cell.com
The rate of change of surface pressure, π, in a Langmuir trough following the deposition of
surfactant suspensions on subphases containing serum, with or without polymers, is used to …
surfactant suspensions on subphases containing serum, with or without polymers, is used to …
[HTML][HTML] More than a monolayer: relating lung surfactant structure and mechanics to composition
C Alonso, T Alig, J Yoon, F Bringezu, H Warriner… - Biophysical …, 2004 - cell.com
Survanta, a clinically used bovine lung surfactant extract, in contact with surfactant in the
subphase, shows a coexistence of discrete monolayer islands of solid phase coexisting with …
subphase, shows a coexistence of discrete monolayer islands of solid phase coexisting with …
Biomechanics of liquid–epithelium interactions in pulmonary airways
SN Ghadiali, DP Gaver - Respiratory physiology & neurobiology, 2008 - Elsevier
The delicate structure of the lung epithelium makes it susceptible to surface tension induced
injury. For example, the cyclic reopening of collapsed and/or fluid-filled airways during the …
injury. For example, the cyclic reopening of collapsed and/or fluid-filled airways during the …
[PDF][PDF] Surfactant proteins SP-A and SP-D in human health and disease
U Kishore, AL Bernal, MF Kamran… - ARCHIVUM …, 2005 - researchgate.net
Summary Surfactant proteins A (SP-A) and D (SP-D) are lung surfactant-associated
hydrophilic proteins that have been implicated in surfactant homeostasis and pulmonary …
hydrophilic proteins that have been implicated in surfactant homeostasis and pulmonary …