Modern medicine has been waging a war on cancer for nearly a century with no tangible
end in sight. Cancer treatments have significantly progressed, but the need to increase …

Following detection of high levels of serum prostate-specific antigen, many men are advised
to have transrectal ultrasound-guided biopsy in an attempt to locate a cancer. This …

Precision medicine was born with the development of new diagnostic techniques and
targeted drugs, yielding better outcomes in cancer care. With the evolution and increasing …

Simple Summary Prostate-specific antigen and digital rectal examination, used to guide
prostate biopsy, often result in overdiagnosis of indolent prostate cancer (PCa) while …

Background Risk stratification in men with suspicion of prostate cancer (PCa) requires
reliable diagnostic tests, not only to identify high-grade PCa, also to minimize the …

This review discusses the most recent evidence for currently available risk stratification tools
in the detection of clinically significant prostate cancer (csPCa), and evaluates diagnostic …

Simple Summary In prostate cancer, overdiagnosis and overtreatment is a common problem
for clinicians. Accurate diagnosis and prognosis are essential to avoid unnecessary biopsy …

Precision medicine has impacted the field of medical oncology by introducing personalized
therapies, improving all measurable outcomes. This field, in turn, has expanded to obtaining …

Prostate cancer (PC) is one of the most common cancers in males and the fifth leading
reason of death. Age, ethnicity, family history, and genetic defects are major factors that …

Importance Multiple strategies integrating magnetic resonance imaging (MRI) and clinical
data have been proposed to determine the need for a prostate biopsy in men with suspected …