Atherosclerosis is a chronic inflammatory disease. Pathophysiological similarities between
chronic infections and atherosclerosis triggered interest in a clinical association between …

Background Macrolide antibiotics (macrolides) are among the most commonly prescribed
antibiotics worldwide and are used for a wide range of infections. However, macrolides also …

Large pragmatic trials provide the most reliable data about the effects of treatments, but
should be designed, analysed, and reported to enable the most effective use of treatments in …

Objectives: To describe the characteristics, treatment, and outcomes of active infective
endocarditis (IE) in Europe. Design: Prospective survey of medical practices in Europe …

Aims Influenza infection has been shown to accentuate the progression of atherosclerosis
and precipitate the occurrence of acute coronary syndrome (ACS). However, the protective …

Background Chlamydia pneumoniae has been found within atherosclerotic plaques, and
elevated titers of antibody to this organism have been linked to a higher risk of coronary …

The role of inflammation in the development of restenosis after percutaneous coronary
interventions has been investigated in several studies. There is an interaction of …

During the past decade, several novel risk factors for atherosclerosis, including inflammation
and infections, have been reported. Seroepidemiological studies suggest an association …

Background There is serological and epidemiological evidence of an association between
Chlamydia pneumoniae infection and coronary artery disease. Results of previous smaller …

Studies reporting an increased risk for cardiac toxicities with macrolide antibiotics have
raised concern regarding their cardiovascular safety. We sought to assess the cardiac safety …