Amyotrophic lateral sclerosis (ALS) is a rare neurological disorder that affects the motor
neurons responsible for regulating muscle movement. However, the molecular pathogenic …

Oxytosis was first described over 30 years ago in nerve cells as a non-excitotoxic pathway
for glutamate-induced cell death. The key steps of oxytosis, including glutathione depletion …

Inonotus obliquus polysaccharide (IOPS) was initially separated and purified via
precipitation from an aqueous extract with 80% alcohol, a DEAE-52 cellulose anion …

Meniere's disease (MD) represents a clinical syndrome characterized by episodes of
spontaneous vertigo, associated with fluctuating, low to medium frequencies sensorineural …

In this study, we hypothesized that anti-parkinsonian effect of puerarin is attributable to its
antioxidant properties via Nrf2-dependent glutathione (GSH) biosynthesis mechanism …

It has been reported that coconut oil supplementation can reduce neuroinflammation.
However, coconut oils are available as virgin coconut oil (VCO), crude coconut oil (ECO) …

Alterations occur in the homeostasis of the transition metals iron (Fe2+) and copper (Cu2+)
during aging and these are further amplified in neurodegenerative diseases, including …

Accumulating evidence suggests that glutathione loss is closely associated with the
progression of neurodegenerative disorders. Here, we found that the neuronal conditional …

Loss of brain glutathione has been associated with cognitive decline and neuronal death
during aging and neurodegenerative diseases. However, whether decreased glutathione …

Simple Summary Ferroptosis is a recently defined form of regulatory cell death. To get a
grasp of the prospective role of ferroptosis in the brain development, we collated ferroptosis …