Background Cervical cancer is the fourth most common cancer in women worldwide, and
arsenic has a certain effect in solid tumor chemotherapy. As the rate-limiting enzyme subunit …

Metabolism and redox signalling share critical nodes in the nervous system. In the last
years, a series of major findings have challenged the current vision on how neural reactive …

Alzheimer's disease is a progressive neurodegenerative disorder leading to cognitive
decline and memory loss. The incidence of this disease continues to increase due to the …

Frontotemporal dementia (FTD) is one of the most prevalent forms of early-onset dementia. It
represents part of the FTD-Amyotrophic Lateral Sclerosis (ALS) spectrum, a continuum of …

Amyotrophic lateral sclerosis (ALS) is a progredient neurodegenerative disease
characterized by a degeneration of the first and second motor neurons. Elevated levels of …

The establishment of antioxidative defense systems might have been mandatory for most
living beings with aerobic metabolisms, because oxygen consumption produces adverse …

The circadian rhythm of the human brain is attuned to sleep-wake cycles that entail global
alterations in neuronal excitability. This periodicity involves a highly coordinated regulation …

Purpose The distal nephron of kidney plays a pivotal role in advancing acute kidney injury
(AKI). Understanding the role of distal nephrons in AKI and identifying markers of injured …

Aging is the biggest risk factor for Parkinson's disease (PD), suggesting that age-related
changes in the brain promote dopamine neuron vulnerability. It is unclear, however, whether …

Oxidative stress has been considered as an important cause of neurocyte damage induced
by carbon monoxide (CO) poisoning; however, the precise mechanisms are not fully …