Current methods to define metabolic tumor volume in positron emission tomography: which one is better?

HJ Im, T Bradshaw, M Solaiyappan, SY Cho - Nuclear medicine and …, 2018 - Springer
Numerous methods to segment tumors using 18 F-fluorodeoxyglucose positron emission
tomography (FDG PET) have been introduced. Metabolic tumor volume (MTV) refers to the …

Therapeutic potential of AMPK signaling targeting in lung cancer: advances, challenges and future prospects

M Ashrafizadeh, S Mirzaei, K Hushmandi… - Life sciences, 2021 - Elsevier
Lung cancer (LC) is a leading cause of death worldwide with high mortality and morbidity. A
wide variety of risk factors are considered for LC development such as smoking, air pollution …

Prognostic value of volumetric parameters of 18F-FDG PET in non-small-cell lung cancer: a meta-analysis

HJ Im, K Pak, GJ Cheon, KW Kang, SJ Kim… - European journal of …, 2015 - Springer
Purpose We conducted a comprehensive systematic review of the literature on volumetric
parameters from 18 F-FDG PET and a meta-analysis of the prognostic value of metabolic …

Deep segmentation networks predict survival of non-small cell lung cancer

S Baek, Y He, BG Allen, JM Buatti, BJ Smith, L Tong… - Scientific reports, 2019 - nature.com
Non-small-cell lung cancer (NSCLC) represents approximately 80–85% of lung cancer
diagnoses and is the leading cause of cancer-related death worldwide. Recent studies …

[HTML][HTML] GLUT5-mediated fructose utilization drives lung cancer growth by stimulating fatty acid synthesis and AMPK/mTORC1 signaling

WL Chen, X Jin, M Wang, D Liu, Q Luo, H Tian, L Cai… - JCI insight, 2020 - ncbi.nlm.nih.gov
Lung cancer (LC) is a leading cause of cancer-related deaths worldwide. Its rapid growth
requires hyperactive catabolism of principal metabolic fuels. It is unclear whether fructose …

The correlation between cell-free DNA and tumour burden was estimated by PET/CT in patients with advanced NSCLC

AD Nygaard, PC Holdgaard, KL Spindler… - British journal of …, 2014 - nature.com
Background: Cell-free DNA (cfDNA) circulating in the blood holds a possible prognostic
value in malignant diseases. Under malignant conditions, the level of cfDNA increases but …

Prognostic value of total lesion glycolysis by 18F-FDG PET/CT in surgically resected stage IA non–small cell lung cancer

SY Park, A Cho, WS Yu, CY Lee, JG Lee… - Journal of Nuclear …, 2015 - Soc Nuclear Med
Despite the favorable prognosis of stage IA non–small cell lung cancer (NSCLC), the
disease recurs after complete surgical resection in 20%–30% of patients. This study …

Recent trends in PET image interpretations using volumetric and texture-based quantification methods in nuclear oncology

MK Rahim, SE Kim, H So, HJ Kim, GJ Cheon… - Nuclear medicine and …, 2014 - Springer
Image quantification studies in positron emission tomography/computed tomography
(PET/CT) are of immense importance in the diagnosis and follow-up of variety of cancers. In …

Metabolic parameters as biomarkers of response to immunotherapy and prognosis in non-small cell lung cancer (NSCLC): a real world experience

L Monaco, M Gemelli, I Gotuzzo, M Bauckneht… - Cancers, 2021 - mdpi.com
Simple Summary The advent of immune-checkpoint inhibitors (ICIs) has significantly
changed the management of patients with non-small cell lung cancer (NSCLC). Although …

18F-FDG PET/CT of Non–Small Cell Lung Carcinoma Under Neoadjuvant Chemotherapy: Background-Based Adaptive-Volume Metrics Outperform TLG and MTV in …

IA Burger, R Casanova, S Steiger… - Journal of Nuclear …, 2016 - Soc Nuclear Med
Assessment of tumor response after chemotherapy using 18F-FDG PET metrics is gaining
acceptance. Several studies have suggested that the parameters metabolically active tumor …