Mammalian zona pellucida glycoproteins: structure and function during fertilization

SK Gupta, B Bhandari, A Shrestha, BK Biswal… - Cell and tissue …, 2012 - Springer
Zona pellucida (ZP) is a glycoproteinaceous translucent matrix that surrounds the
mammalian oocyte and plays a critical role in the accomplishment of fertilization. In humans …

[HTML][HTML] Human zona pellucida glycoproteins: binding characteristics with human spermatozoa and induction of acrosome reaction

SK Gupta - Frontiers in cell and developmental biology, 2021 - frontiersin.org
Human zona pellucida (ZP) matrix is composed of four glycoproteins designated as ZP
glycoprotein-1 (ZP1),-2 (ZP2),-3 (ZP3), and-4 (ZP4). Mutations in the genes encoding human …

Novel mutations in ZP1, ZP2, and ZP3 cause female infertility due to abnormal zona pellucida formation

Z Zhou, C Ni, L Wu, B Chen, Y Xu, Z Zhang, J Mu, B Li… - Human Genetics, 2019 - Springer
The human zona pellucida (ZP) is an extracellular glycoprotein matrix composed of ZP1,
ZP2, ZP3, and ZP4 surrounding the oocyte, and it plays an important role in sperm–egg …

[HTML][HTML] Mutant ZP1 in familial infertility

HL Huang, C Lv, YC Zhao, W Li, XM He… - … England Journal of …, 2014 - Mass Medical Soc
The human zona pellucida is composed of four glycoproteins (ZP1, ZP2, ZP3, and ZP4) and
has an important role in reproduction. Here we describe a form of infertility with an …

The human egg's zona pellucida

SK Gupta - Current topics in developmental biology, 2018 - Elsevier
Human zona pellucida (ZP) matrix, a delicate network of thin interconnected filaments, is
primarily composed of four glycoproteins, namely, ZP1, ZP2, ZP3, and ZP4. All four zona …

[HTML][HTML] New insights into the mammalian egg zona pellucida

C Moros-Nicolás, P Chevret… - International Journal of …, 2021 - mdpi.com
Mammalian oocytes are surrounded by an extracellular coat called the zona pellucida (ZP),
which, from an evolutionary point of view, is the most ancient of the coats that envelope …

Non-invasive oocyte quality assessment

R Sciorio, D Miranian, GD Smith - Biology of Reproduction, 2022 - academic.oup.com
Oocyte quality is perhaps the most important limiting factor in female fertility; however, the
current methods of determining oocyte competence are only marginally capable of …

Dynamic regulation of sperm interactions with the zona pellucida prior to and after fertilisation

BM Gadella - Reproduction, Fertility and Development, 2012 - CSIRO Publishing
Recent findings have refined our thinking on sperm interactions with the cumulus–oocyte
complex (COC) and our understanding of how, at the molecular level, the sperm cell …

Novel mutations in ZP2 and ZP3 cause female infertility in three patients

W Jia, Q Xi, L Zhu, Y Luo, Z Li, M Hou, D Zhang… - Journal of Assisted …, 2022 - Springer
Purpose The aim of this study was to identify the disease-causing mutations found in three
infertile female patients who were diagnosed with abnormal zona pellucida (ZP) and empty …

Rabbit zona pellucida composition: a molecular, proteomic and phylogenetic approach

I Stetson, MJ Izquierdo-Rico, C Moros, P Chevret… - Journal of …, 2012 - Elsevier
The zona pellucida (ZP) participates in sperm–egg interactions during the first steps of
fertilization. Recent studies have shown that the ZP matrix of oocytes in several species is …