The current management of acute coronary syndromes (ACS) is with an invasive strategy to
guide treatment. However, identifying the lesions which are physiologically significant can …

Background: Quantification of coronary blood flow is used to evaluate coronary artery
disease, but our understanding of flow through branched systems is poor. Murray's law …

Background Increased coronary microvascular resistance (CMVR) is associated with
coronary microvascular dysfunction (CMD). Although CMD is more common in women, sex …

Three dimensional (3D) coronary anatomy, reconstructed from coronary angiography (CA),
is now being used as the basis to compute 'virtual'fractional flow reserve (vFFR), and thereby …

Aims Ischaemic heart disease results from insufficient coronary blood flow. Direct
measurement of absolute flow (mL/min) is feasible, but has not entered routine clinical …

Background: Myocardial ischaemia results from insufficient coronary blood flow. Computed
virtual fractional flow reserve (vFFR) allows quantification of proportional flow loss without …

Aims To extend the benefits of physiologically guided percutaneous coronary intervention to
many more patients, angiography-derived, or 'virtual'fractional flow reserve (vFFR) has been …

Fractional flow reserve (FFR) is the current gold standard invasive assessment of coronary
artery disease (CAD). FFR reports coronary blood flow (CBF) as a fraction of a hypothetical …

Objective Coronary artery disease (CAD) is a debilitating condition that can lead to
myocardial infarction (MI). Exosomal miRNAs (exo‐miRNA) can be diagnostic biomarkers …

In this study, dictionary learning and expectation maximization reconstruction (DLEM) was
combined to denoise 64‐slice spiral CT images, and results of coronary angiography (CAG) …