Phenotype-specific treatment of heart failure with preserved ejection fraction: a multiorgan roadmap

SJ Shah, DW Kitzman, BA Borlaug, L Van Heerebeek… - Circulation, 2016 - Am Heart Assoc
Heart failure (HF) with preserved ejection fraction (EF; HFpEF) accounts for 50% of HF
cases, and its prevalence relative to HF with reduced EF continues to rise. In contrast to HF …

A novel paradigm for heart failure with preserved ejection fraction: comorbidities drive myocardial dysfunction and remodeling through coronary microvascular …

WJ Paulus, C Tschöpe - Journal of the American College of Cardiology, 2013 - jacc.org
Over the past decade, myocardial structure, cardiomyocyte function, and intramyocardial
signaling were shown to be specifically altered in heart failure with preserved ejection …

Angiogenesis and cardiac hypertrophy: maintenance of cardiac function and causative roles in heart failure

T Oka, H Akazawa, AT Naito, I Komuro - Circulation research, 2014 - Am Heart Assoc
Cardiac hypertrophy is an adaptive response to physiological and pathological overload. In
response to the overload, individual cardiac myocytes become mechanically stretched and …

Recommendations on the use of echocardiography in adult hypertension: a report from the European Association of Cardiovascular Imaging (EACVI) and the …

TH Marwick, TC Gillebert, G Aurigemma… - European Heart …, 2015 - academic.oup.com
Hypertension remains a major contributor to the global burden of disease. The
measurement of blood pressure continues to have pitfalls related to both physiological …

Sex‐specific cardiovascular structure and function in heart failure with preserved ejection fraction

M Gori, CSP Lam, DK Gupta… - European journal of …, 2014 - Wiley Online Library
Aims Women are more likely to develop heart failure with preserved ejection fraction
(HFpEF) than men. We studied the relationship between sex and cardiovascular structure …

Phenotyping the hypertensive heart

M Tadic, C Cuspidi, TH Marwick - European heart journal, 2022 - academic.oup.com
Arterial hypertension remains the most frequent cardiovascular (CV) risk factor, and is
responsible for a huge global burden of disease. Echocardiography is the first-line imaging …

Associations of accelerometer‐based sedentary time, light physical activity and moderate‐to‐vigorous physical activity with resting cardiac structure and function in …

AO Agbaje - Scandinavian Journal of Medicine & Science in …, 2023 - Wiley Online Library
Background This study examined the independent relationships of device‐based measured
sedentary time (ST) and physical activity (PA) in relation to cardiac structural and functional …

Diabetic cardiomyopathy: prevalence, determinants and potential treatments

GS Gulsin, L Athithan… - Therapeutic advances in …, 2019 - journals.sagepub.com
The prevalence of type 2 diabetes (T2D) has reached a pandemic scale. These patients are
at a substantially elevated risk of developing cardiovascular disease, with heart failure (HF) …

The right ventricle explains sex differences in survival in idiopathic pulmonary arterial hypertension

W Jacobs, MC van de Veerdonk, P Trip, F de Man… - Chest, 2014 - Elsevier
Background Male sex is an independent predictor of worse survival in pulmonary arterial
hypertension (PAH). This finding might be explained by more severe pulmonary vascular …

Aerobic exercise training promotes physiological cardiac remodeling involving a set of microRNAs

T Fernandes, VG Baraúna… - American Journal …, 2015 - journals.physiology.org
Left ventricular (LV) hypertrophy is an important physiological compensatory mechanism in
response to chronic increase in hemodynamic overload. There are two different forms of LV …