Which form is that? The importance of selenium speciation and metabolism in the prevention and treatment of disease

CM Weekley, HH Harris - Chemical Society Reviews, 2013 - pubs.rsc.org
The biological activity of selenium is dependent upon its speciation. We aim to integrate
selenium speciation and metabolism into a discussion of the mechanisms by which …

Organoselenium and organotellurium compounds: toxicology and pharmacology

CW Nogueira, G Zeni, JBT Rocha - Chemical reviews, 2004 - ACS Publications
Organoselenium compounds have found such wide utility because of their effects on an
extraordinary number of very different reactions, including many carbon-carbon bond …

Toxicology and pharmacology of selenium: emphasis on synthetic organoselenium compounds

CW Nogueira, JBT Rocha - Archives of Toxicology, 2011 - Springer
The advance in the area of synthesis and reactivity of organoselenium, as well as the
discovery that selenium was the cause of severe intoxication episodes of livestock in the …

Antioxidant activity of sulfur and selenium: a review of reactive oxygen species scavenging, glutathione peroxidase, and metal-binding antioxidant mechanisms

EE Battin, JL Brumaghim - Cell biochemistry and biophysics, 2009 - Springer
It is well known that oxidation caused by reactive oxygen species (ROS) is a major cause of
cellular damage and death and has been implicated in cancer, neurodegenerative, and …

Medicinal mushroom modulators of molecular targets as cancer therapeutics

BZ Zaidman, M Yassin, J Mahajna… - Applied Microbiology and …, 2005 - Springer
Empirical approaches to discover anticancer drugs and cancer treatments have made
limited progress in the past several decades in finding a cure for cancer. The expanded …

Protection of cisplatin-induced spermatotoxicity, DNA damage and chromatin abnormality by selenium nano-particles

MA Rezvanfar, MA Rezvanfar, AR Shahverdi… - Toxicology and applied …, 2013 - Elsevier
Cisplatin (CIS), an anticancer alkylating agent, induces DNA adducts and effectively cross
links the DNA strands and so affects spermatozoa as a male reproductive toxicant. The …

Potential oxidative stress of gold nanoparticles by induced-NO releasing in serum

HY Jia, Y Liu, XJ Zhang, L Han, LB Du… - Journal of the …, 2009 - ACS Publications
Nitric oxide (NO)-release in blood serum initiated by gold nanoparticles has been prove to
be a reaction between RSNO and the gold nanoparitcles. In this reaction the NO production …

GPx-Like activity of selenides and selenoxides: Experimental evidence for the involvement of hydroxy perhydroxy selenane as the active species

V Nascimento, EE Alberto, DW Tondo… - Journal of the …, 2012 - ACS Publications
The reaction mechanism of the GPx-like oxidation of PhSH with H2O2 catalyzed by
selenoxides proceeds via formation of the hydroxy perhydroxy selenane, which is a stronger …

Oxidative stress following exposure to silver and gold nanoparticles in mice

R Shrivastava, P Kushwaha… - … and industrial health, 2016 - journals.sagepub.com
Silver (Ag) and gold nanoparticles (Au NPs) have wide applications. They are increasingly
being used in the medical devices, biosensors, cancer cell imaging, and cosmetics …

Rapid, room-temperature synthesis of amorphous selenium/protein composites using Capsicum annuum L extract

S Li, Y Shen, A Xie, X Yu, X Zhang, L Yang… - Nanotechnology, 2007 - iopscience.iop.org
We describe the formation of amorphous selenium (α-Se)/protein composites using
Capsicum annuum L extract to reduce selenium ions (SeO 3 2−) at room temperature. The …