Stroke is a leading cause of death and disability worldwide, and approximately 87% of
cases are attributed to ischemia. The main factors that cause ischemic stroke include …

The gut microbiota is symbiotic with the human host and has been extensively studied in
recent years resulting in increasing awareness of the effects of the gut microbiota on human …

Background Formononetin is a type of phytoestrogen obtained from the Chinese medical
herb Red Clover. It exhibits anti-neoplastic hepatoprotective, and neuroprotective properties …

Background Microglia/macrophages are activated after cerebral ischemic stroke and can
contribute to either brain injury or recovery by polarizing microglia/macrophage into …

Ischemic stroke (IS) is a common neurological disorder associated with high disability rates
and mortality rates. At present, recombinant tissue plasminogen activator (r-tPA) is the only …

Background Neuroinflammation has been reported as a potential contributing factor to brain
diseases, and is characterized by activated microglia with release of multiple inflammatory …

The inflammatory response after cerebral ischemia/reperfusion is an important cause of
neurological damage and repair. After cerebral ischemia/reperfusion, microglia are …

Stroke is a threatening cerebrovascular disease caused by thrombus with high morbidity
and mortality rates. Neutrophils are the first to be recruited in the brain after stroke, which …

Nicotinamide phosphoribosyltransferase (NAMPT) maintains mitochondrial function and
protects against cerebral ischemic injury by improving energy metabolism. Notoginsenoside …

Highlights•Recent advances in bioproduction aroma compounds are reviewed.•Most
microbial processes are with engineered microorganisms.•Aroma production with isolated …