Environmental and human health challenges of industrial livestock and poultry farming in China and their mitigation

Y Hu, H Cheng, S Tao - Environment international, 2017 - Elsevier
Driven by the growing demand for food products of animal origin, industrial livestock and
poultry production has become increasingly popular and is on the track of becoming an …

Metagenomic and network analysis reveal wide distribution and co-occurrence of environmental antibiotic resistance genes

B Li, Y Yang, L Ma, F Ju, F Guo, JM Tiedje… - The ISME …, 2015 - academic.oup.com
A metagenomic approach and network analysis was used to investigate the wide-spectrum
profiles of antibiotic resistance genes (ARGs) and their co-occurrence patterns in 50 …

An integrated catalog of reference genes in the human gut microbiome

J Li, H Jia, X Cai, H Zhong, Q Feng, S Sunagawa… - Nature …, 2014 - nature.com
Many analyses of the human gut microbiome depend on a catalog of reference genes.
Existing catalogs for the human gut microbiome are based on samples from single cohorts …

Machine learning meta-analysis of large metagenomic datasets: tools and biological insights

E Pasolli, DT Truong, F Malik, L Waldron… - PLoS computational …, 2016 - journals.plos.org
Shotgun metagenomic analysis of the human associated microbiome provides a rich set of
microbial features for prediction and biomarker discovery in the context of human diseases …

What is a resistance gene? Ranking risk in resistomes

JL Martínez, TM Coque, F Baquero - Nature Reviews Microbiology, 2015 - nature.com
Metagenomic studies have shown that antibiotic resistance genes are ubiquitous in the
environment, which has led to the suggestion that there is a high risk that these genes will …

Interconnected microbiomes and resistomes in low-income human habitats

EC Pehrsson, P Tsukayama, S Patel, M Mejía-Bautista… - Nature, 2016 - nature.com
Antibiotic-resistant infections annually claim hundreds of thousands of lives worldwide. This
problem is exacerbated by exchange of resistance genes between pathogens and benign …

A reservoir of 'historical'antibiotic resistance genes in remote pristine Antarctic soils

MW Van Goethem, R Pierneef, OKI Bezuidt… - Microbiome, 2018 - Springer
Background Soil bacteria naturally produce antibiotics as a competitive mechanism, with a
concomitant evolution, and exchange by horizontal gene transfer, of a range of antibiotic …

Deciphering of microbial community and antibiotic resistance genes in activated sludge reactors under high selective pressure of different antibiotics

R Zhao, J Feng, J Liu, W Fu, X Li, B Li - Water Research, 2019 - Elsevier
Currently, the effects of high antibiotic concentrations on the performance of microbiota and
antibiotic resistance genes (ARGs) in activated sludge (AS) process are not well …

The structure and diversity of human, animal and environmental resistomes

C Pal, J Bengtsson-Palme, E Kristiansson… - Microbiome, 2016 - Springer
Abstract Background Antibiotic resistance genes (ARGs) are widespread but cause
problems only when present in pathogens. Environments where selection and transmission …

Dissemination of the mcr-1 colistin resistance gene

AO Olaitan, S Chabou, L Okdah, S Morand… - The Lancet infectious …, 2016 - thelancet.com
1 Liu YY, Wang Y, Walsh TR, et al. Emergence of plasmid-mediated colistin resistance
mechanism MCR-1 in animals and human beings in China: a microbiological and molecular …