[HTML][HTML] Mitochondrial dysfunction and oxidative stress in metabolic disorders—A step towards mitochondria based therapeutic strategies

JS Bhatti, GK Bhatti, PH Reddy - … et Biophysica Acta (BBA)-Molecular Basis …, 2017 - Elsevier
Mitochondria are the powerhouses of the cell and are involved in essential functions of the
cell, including ATP production, intracellular Ca 2+ regulation, reactive oxygen species …

The role of antioxidants in the chemistry of oxidative stress: A review

AM Pisoschi, A Pop - European journal of medicinal chemistry, 2015 - Elsevier
Abstract This Review Article is focused on the action of the reactive oxygenated species in
inducing oxidative injury of the lipid membrane components, as well as on the ability of …

Role of mitochondrial dysfunction, oxidative stress and autophagy in progression of Alzheimer's disease

V Bhatia, S Sharma - Journal of the neurological sciences, 2021 - Elsevier
Alzheimer's disease (AD) is the most common form of dementia. The pathological hallmarks
of AD are amyloid plaques [aggregates of amyloid beta (A)] and neurofibrillary tangles …

Naturally occurring antioxidant therapy in Alzheimer's disease

AE Collins, TM Saleh, BE Kalisch - Antioxidants, 2022 - mdpi.com
It is estimated that the prevalence rate of Alzheimer's disease (AD) will double by the year
2040. Although currently available treatments help with symptom management, they do not …

Role of oxidative stress and antioxidants in daily nutrition and human health

G Bjørklund, S Chirumbolo - Nutrition, 2017 - Elsevier
Diet is a complex process that we are just beginning to fully understand. We need to develop
a deeper comprehension of metabolism, energy balance, the molecular pathways involved …

Use of curcumin in diagnosis, prevention, and treatment of Alzheimer's disease

M Chen, ZY Du, X Zheng, DL Li, RP Zhou… - Neural regeneration …, 2018 - journals.lww.com
This review summarizes and describes the use of curcumin in diagnosis, prevention, and
treatment of Alzheimer's disease. For diagnosis of Alzheimer's disease, amyloid-β and …

Effects of cannabidiol interactions with Wnt/β-catenin pathway and PPARγ on oxidative stress and neuroinflammation in Alzheimer's disease

A Vallée, Y Lecarpentier, R Guillevin… - Acta biochimica et …, 2017 - academic.oup.com
Alzheimer's disease (AD) is a neurodegenerative disease, in which the primary etiology
remains unknown. AD presents amyloid beta (Aβ) protein aggregation and neurofibrillary …

The link between Alzheimer disease and metabolic syndrome: a mutual relationship and long rigorous investigation

HM Al-Kuraishy, MS Jabir, AK Albuhadily… - Ageing Research …, 2023 - Elsevier
It has been illustrated that metabolic syndrome (MetS) is associated with Alzheimer disease
(AD) neuropathology. Components of MetS including central obesity, hypertension, insulin …

Ceramides in Alzheimer's Disease: Key Mediators of Neuronal Apoptosis Induced by Oxidative Stress and Aβ Accumulation

M Jazvinšćak Jembrek, PR Hof… - Oxidative medicine and …, 2015 - Wiley Online Library
Alzheimer's disease (AD), the most common chronic and progressive neurodegenerative
disorder, is characterized by extracellular deposits of amyloid β‐peptides (Aβ) and …

Cerebrospinal fluid biomarkers of Alzheimer's disease: current evidence and future perspectives

DA McGrowder, F Miller, K Vaz, C Nwokocha… - Brain sciences, 2021 - mdpi.com
Alzheimer's disease is a progressive, clinically heterogeneous, and particularly complex
neurodegenerative disease characterized by a decline in cognition. Over the last two …