[HTML][HTML] Polycystic ovary syndrome: etiology, current management, and future therapeutics

S Singh, N Pal, S Shubham, DK Sarma… - Journal of Clinical …, 2023 - mdpi.com
Polycystic ovary syndrome (PCOS) is a complex endocrine and metabolic disorder, typically
characterized by anovulation, infertility, obesity, insulin resistance, and polycystic ovaries …

[HTML][HTML] Sex hormone-binding globulin (SHBG) as an early biomarker and therapeutic target in polycystic ovary syndrome

X Qu, R Donnelly - International journal of molecular sciences, 2020 - mdpi.com
Human sex hormone-binding globulin (SHBG) is a glycoprotein produced by the liver that
binds sex steroids with high affinity and specificity. Clinical observations and reports in the …

[HTML][HTML] Is melatonin the “next vitamin D”?: a review of emerging science, clinical uses, safety, and dietary supplements

DM Minich, M Henning, C Darley, M Fahoum… - Nutrients, 2022 - mdpi.com
Nutrients | Free Full-Text | Is Melatonin the “Next Vitamin D”?: A Review of
Emerging Science, Clinical Uses, Safety, and Dietary Supplements Next Article in Journal …

[HTML][HTML] Mechanisms of and potential medications for oxidative stress in ovarian granulosa cells: a review

S Liu, Y Jia, S Meng, Y Luo, Q Yang, Z Pan - International Journal of …, 2023 - mdpi.com
Granulosa cells are essential for follicle initiation and development, and their abnormal
function or apoptosis is a crucial factor leading to follicular atresia. A state of oxidative stress …

[HTML][HTML] Ketogenic diet as medical prescription in women with polycystic ovary syndrome (PCOS)

L Barrea, L Verde, E Camajani, S Cernea… - Current Nutrition …, 2023 - Springer
Abstract Purpose of Review The polycystic ovary syndrome (PCOS) is an endocrine
dysfunction associated with a myriad of metabolic disorders and high rate of infertility. In …

[HTML][HTML] Improvement effect of metformin on female and male reproduction in endocrine pathologies and its mechanisms

AO Shpakov - Pharmaceuticals, 2021 - mdpi.com
Metformin (MF), a first-line drug to treat type 2 diabetes mellitus (T2DM), alone and in
combination with other drugs, restores the ovarian function in women with polycystic ovary …

The role of genetics, epigenetics and lifestyle in polycystic ovary syndrome development: the state of the art

V Bruni, A Capozzi, S Lello - Reproductive Sciences, 2022 - Springer
Polycystic ovary syndrome (PCOS) is an endocrine-metabolic disease affecting about 20–
25% of women in reproductive age. Different mechanisms could contribute to the …

[HTML][HTML] Estrogen receptors in polycystic ovary syndrome

XL Xu, SL Deng, ZX Lian, K Yu - Cells, 2021 - mdpi.com
Female infertility is mainly caused by ovulation disorders, which affect female reproduction
and pregnancy worldwide, with polycystic ovary syndrome (PCOS) being the most prevalent …

An update on polycystic ovary syndrome: A review of the current state of knowledge in diagnosis, genetic etiology, and emerging treatment options

H Islam, J Masud, YN Islam, FKM Haque - Women's Health, 2022 - journals.sagepub.com
Polycystic ovary syndrome is the most common endocrine disorder in women of
reproductive age, which is still incurable. However, the symptoms can be successfully …

[HTML][HTML] Mitochondrial dysfunction in PCOS: insights into Reproductive Organ Pathophysiology

KM Siemers, AK Klein, ML Baack - International Journal of Molecular …, 2023 - mdpi.com
Polycystic ovary syndrome (PCOS) is a complex, but relatively common endocrine disorder
associated with chronic anovulation, hyperandrogenism, and micro-polycystic ovaries. In …