Metastasis of tumor cells is a complex challenge and significantly diminishes the overall
survival and prognosis of cancer patients. The epithelial‐to‐mesenchymal transition (EMT) …

Lung cancer is one of the common malignant tumors that threaten human life with serious
incidence and high mortality. According to the histopathological characteristics, lung cancer …

Epithelial–mesenchymal plasticity (EMP) plays critical roles during embryonic development,
wound repair, fibrosis, inflammation and cancer. During cancer progression, EMP results in …

Background and Aims Circulating albumin in cirrhosis can be dysfunctional because of
accumulating structural damages, leading to the concept of effective albumin concentration …

Immune checkpoint inhibitors (ICIs) are new and promising therapeutic agents for non-small
cell lung cancer (NSCLC). However, along with demonstrating remarkable efficacy, ICIs can …

Inflammation has accompanied human beings since the emergence of wounds and
infections. In the past decades, numerous efforts have been undertaken to explore the …

Background and Aims Liver ischemia reperfusion injury (IRI) remains an unresolved clinical
problem. This study dissected roles of liver‐resident macrophage Kupffer cells (KCs), with a …

Background Pulmonary fibrosis is the deadliest manifestation of connective tissue disease
(CTD). Iguratimod (IGU) is a new drug that is used for controlling CTD. Clinical studies have …

octylphenol (4-OP), a toxic estrogenic environmental pollutant, can threaten aquatic animal
and human health. However, toxic effect of 4-OP on fish has not been reported. To …

Mitochondrial function and homeostasis are critical to the proliferation of lung cancer cells. T-
cell immunoglobulin and mucin domain-containing molecule 4 (TIM-4) promotes the …