[HTML][HTML] Vaccine adjuvants: mechanisms and platforms

T Zhao, Y Cai, Y Jiang, X He, Y Wei, Y Yu… - Signal transduction and …, 2023 - nature.com
Adjuvants are indispensable components of vaccines. Despite being widely used in
vaccines, their action mechanisms are not yet clear. With a greater understanding of the …

[HTML][HTML] Biosafety of mesoporous silica nanoparticles; towards clinical translation

A Lérida-Viso, A Estepa-Fernández… - Advanced Drug Delivery …, 2023 - Elsevier
Mesoporous silica nanoparticles (MSNs) have attracted the attention of chemists, who have
developed numerous systems for the encapsulation of a plethora of molecules, allowing the …

[HTML][HTML] Recent advances in functionalized nanoparticles in cancer theranostics

S Siddique, JCL Chow - Nanomaterials, 2022 - mdpi.com
Cancer theranostics is the combination of diagnosis and therapeutic approaches for cancer,
which is essential in personalized cancer treatment. The aims of the theranostics application …

[HTML][HTML] A systemic review on development of mesoporous nanoparticles as a vehicle for transdermal drug delivery

P Kolimi, S Narala, AAA Youssef, D Nyavanandi… - …, 2023 - ncbi.nlm.nih.gov
Recent advances in drug delivery technologies utilizing a variety of carriers have resulted in
a paradigm shift in the current approach to diagnosis and therapy. Mesoporous silica …

Delivery of curcumin by fucoidan-coated mesoporous silica nanoparticles: Fabrication, characterization, and in vitro release performance

X Zhang, Y Zhu, L Fan, J Ling, LY Yang, N Wang… - International Journal of …, 2022 - Elsevier
Mesoporous silica nanoparticles (MSN) are effective drug delivery carriers because of their
adjustable large pore size and high porosity. In this study, complex nanoparticles containing …

[HTML][HTML] Natural biopolymers as smart coating materials of mesoporous silica nanoparticles for drug delivery

B Dumontel, V Conejo-Rodríguez, M Vallet-Regí… - Pharmaceutics, 2023 - mdpi.com
In recent years, the functionalization of mesoporous silica nanoparticles (MSNs) with
different types of responsive pore gatekeepers have shown great potential for the …

Tuning mesoporous silica nanoparticles in novel avenues of cancer therapy

S Shah, P Famta, D Bagasariya… - Molecular …, 2022 - ACS Publications
The global menace of cancer has led to an increased death toll in recent years. The constant
evolution of cancer therapeutics with novel delivery systems has paved the way for …

Drug delivery to the inflamed intestinal mucosa–targeting technologies and human cell culture models for better therapies of IBD

O Hartwig, MAS Boushehri, KS Shalaby… - Advanced Drug Delivery …, 2021 - Elsevier
Current treatment strategies for inflammatory bowel disease (IBD) seek to alleviate the
undesirable symptoms of the disorder. Despite the higher specificity of newer generation …

Active targeting significantly outperforms nanoparticle size in facilitating tumor-specific uptake in orthotopic pancreatic cancer

WM MacCuaig, BL Fouts, MW McNally… - … applied materials & …, 2021 - ACS Publications
Nanoparticles are widely studied as theranostic vehicles for cancer; however, clinical
translation has been limited due to poor tumor specificity. Features that maximize tumor …

Mesoporous silica nanoparticles as carrier to overcome bacterial drug resistant barriers

J Zhuang, Y Yu, R Lu - International Journal of Pharmaceutics, 2023 - Elsevier
Antibiotic resistance has become a global threat to health due to abuse of antibiotics. Lots of
existing antibiotics have lost their effect on drug resistant bacteria. Moreover, the discovery …