The rise in fluorescence-based imaging techniques over the past 3 decades has improved
the ability of researchers to scrutinize live cell biology at increased spatial and temporal …

Background Colitis‐associated cancer (CAC) is one of the most severe complications of
inflammatory bowel disease (IBD), which has caused a worse survival rate in IBD patients …

Antibiotic resistance is on the rise and has become one of the biggest public health
challenges of our time. Bacteria are able to adapt to the selective pressure exerted by …

The bactericidal effects of antibiotics are undoubtedly triggered by target-specific
interactions, but there is growing evidence that an important aspect of cytotoxicity results …

Recent studies show that triclosan (TCS) exposure causes reduction in pigments,
suppression of photosynthesis, and induction of oxidative stress at the physiological level …

Proofreading during DNA replication and post-replication mismatch repair are two major
defenses against mutations. Foster et al. and Niccum et al. used mutation accumulation and …

DNA repair mechanisms fulfil a dual role, as they are essential for cell survival and genome
maintenance. Here, we studied how cells regulate the interplay between DNA repair and …

Numerous lethal stresses in bacteria including antibiotics, thymineless death, and MalE-
LacZ expression trigger an increase in the production of reactive oxygen species. This …

A recent study shows that high expression of the efflux-pump AcrAB-TolC, which increases
antibiotic tolerance, reduces DNA mismatch repair in Escherichia coli to promote …

Translesion synthesis (TLS) is a highly conserved mutagenic DNA lesion tolerance pathway,
which employs specialized, low-fidelity DNA polymerases to synthesize across lesions …