Cholesterol metabolism: physiological regulation and diseases
J Guo, S Chen, Y Zhang, J Liu, L Jiang, L Hu… - MedComm, 2024 - Wiley Online Library
Cholesterol homeostasis is crucial for cellular and systemic function. The disorder of
cholesterol metabolism not only accelerates the onset of cardiovascular disease (CVD) but …
cholesterol metabolism not only accelerates the onset of cardiovascular disease (CVD) but …
The regulatory role of MicroRNAs on phagocytes: a potential therapeutic target for chronic diseases
Y Wang, X Liu, P Xia, Z Li, X FuChen, Y Shen… - Frontiers in …, 2022 - frontiersin.org
An effective acute inflammatory response results in the elimination of infectious
microorganisms, followed by a smooth transition to resolution and repair. During the …
microorganisms, followed by a smooth transition to resolution and repair. During the …
[HTML][HTML] Inhibition of PHLPP2/cyclin D1 protein translation contributes to the tumor suppressive effect of NFκB2 (p100)
J Xu, Y Wang, X Hua, J Xu, Z Tian, H Jin, J Li, XR Wu… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Although the precursor protein of NFκB2 (p100) is thought to act as a tumor suppressor in
mammalian cells, the molecular mechanism of its anti-tumor activity is far from clear. Here …
mammalian cells, the molecular mechanism of its anti-tumor activity is far from clear. Here …
CFTR protects against vascular inflammation and atherogenesis in apolipoprotein E-deficient mice
Z Li, Z Shen, H Xue, S Cheng, Q Ji, Y Liu… - Bioscience …, 2017 - portlandpress.com
Atherosclerosis is a chronic inflammatory disease of the vascular wall. Dysfunction of cystic
fibrosis transmembrane conductance regulator (CFTR) has been shown to result in …
fibrosis transmembrane conductance regulator (CFTR) has been shown to result in …
Ablation of miR-144 increases vimentin expression and atherosclerotic plaque formation
Q He, F Wang, T Honda, KD Greis, AN Redington - Scientific Reports, 2020 - nature.com
It has been suggested that miR-144 is pro-atherosclerotic via effects on reverse cholesterol
transportation targeting the ATP binding cassette protein. This study used proteomic …
transportation targeting the ATP binding cassette protein. This study used proteomic …
Cardioprotective effects of high‐intensity interval training are mediated through microRNA regulation of mitochondrial and oxidative stress pathways
N Jeremic, GJ Weber, NT Theilen… - Journal of cellular …, 2020 - Wiley Online Library
Human studies have shown high‐intensity interval training (HIIT) has beneficial
cardiovascular effects and is typically more time‐efficient compared with traditional …
cardiovascular effects and is typically more time‐efficient compared with traditional …
[HTML][HTML] Possible role of MicroRNA in equine insulin resistance: A pilot study
H da Costa Santos, T Hess, J Bruemmer… - Journal of equine …, 2018 - Elsevier
MicroRNAs (miRNAs) are a class of small endogenous single-stranded noncoding RNA
molecules that have important roles in several biological processes. Research in human …
molecules that have important roles in several biological processes. Research in human …
MicroRNA-mediated MMP regulation: current diagnostic and therapeutic strategies for metabolic syndrome
Introduction: Metabolic Syndrome (MS) is a global socioeconomic problem rapidly
progressing in accordance with increasing Body Mass Index (BMI) and age. It is a …
progressing in accordance with increasing Body Mass Index (BMI) and age. It is a …
外泌体microRNA 在心血管疾病中的研究进展及其法医学应用前景.
马晓楠, 路陆, 黄琰潼, 岑昌谦… - Journal of Forensic …, 2022 - search.ebscohost.com
外泌体微小RNA (microRNA, miRNA) 是由外泌体介导以实现细胞间通讯的miRNA,
在生物体内广泛存在. 近年来, 外泌体miRNA 的多重生物学功能在心血管疾病发生 …
在生物体内广泛存在. 近年来, 外泌体miRNA 的多重生物学功能在心血管疾病发生 …
HDL and MicroRNAs
H Cui, K Lv, N Yang - HDL Metabolism and Diseases, 2022 - Springer
In previous chapters, we know that high-density lipoproteins (HDLs) could act at multiple cell
lines and then trigger intracellular molecular pathway to prevent several metabolic diseases …
lines and then trigger intracellular molecular pathway to prevent several metabolic diseases …