The heterogeneity of asthma makes it challenging to unravel the pathophysiologic
mechanisms of the disease. Despite the wealth of research identifying diverse phenotypes …

Nuclear factor erythroid 2-related factor 2 (Nrf2) is a major transcription factor involved in
redox homeostasis and in the response induced by oxidative injury. Nrf2 is present in an …

Cells constantly produce oxidizing species because of their metabolic activity, which is
counteracted by the continuous production of antioxidant species to maintain the …

Oxidative stress participates in the development and exacerbation of cardiovascular
diseases (CVD). The ability to promptly quantify an imbalance in an individual reductive …

Introduction Severe eosinophilic asthma is characterised by frequent exacerbations and a
relative insensitivity to steroids. Experimentally, smoking may induce eosinophilic airway …

Simple Summary This review is focused on the role of oxidative stress in childhood asthma.
The term “oxidative stress" indicates an imbalance between production of radical oxygen …

Electronic nicotine delivery systems (ENDS) may reduce health risks associated with chronic
exposure to smoke and their potential benefits have been the matter of intense scientific …

Asthma is considered a chronic inflammatory disorder associated with airway
hyperresponsiveness (AHR). Increased oxidative stress (OS) is a clinical feature of asthma …

Background. Imbalanced oxidative stress and antioxidant defense are involved in airway
remodeling in asthma. It has been demonstrated that Tetrandrine has a potent role in …

To inform the clinical practice guidelines' recommendations developed by the European
Academy of Allergy and Clinical Immunology systematic reviews (SR) assessed using …