Reactive oxygen species (ROS) are a chemically defined group of reactive molecules
derived from molecular oxygen. ROS are involved in a plethora of processes in cells in all …

Classically, superoxide anion O2•− and reactive oxygen species ROS play a dual role. At
the physiological balance level, they are a by-product of O2 reduction, necessary for cell …

Galectin-3 (Gal-3) is a β-galactoside-binding protein belonging to the lectin family with
pleiotropic regulatory activities and several physiological cellular functions, such as cellular …

Intracellular bacteria in latent or dormant states tolerate high‐dose antibiotics. Fighting
against these opportunistic bacteria has been a long‐standing challenge. Herein, the design …

La evolución entre la infección por Mycobacterium tuberculosis y la tuberculosis activa es
multifactorial e implica diferentes escalas biológicas. La síntesis de ESAT-6 o la inducción …

Internalization of Staphylococcus aureus by macrophages can inactivate bacterial killing
mechanisms, allowing intracellular residence and dissemination of infection. Concurrently …

Long-term antimicrobial therapies are necessary to treat infections caused by virulent
intracellular pathogens, including biothreat agents. Current treatment plans include …

Antimicrobial peptides (AMPs) have been described as excellent candidates to overcome
antibiotic resistance. Frequently, AMPs exhibit a wide therapeutic window, with low …

Autophagy is a well-conserved lysosomal degradation pathway that plays key roles in
bacterial infections. One of the most studied is probably xenophagy, the selective capture …

Bacterial infections caused by intracellular pathogens are difficult to control. Conventional
antibiotic therapies are often ineffective, as high doses are needed to increase the number …