Recent advances in antifungal drug development targeting lanosterol 14α‐demethylase (CYP51): a comprehensive review with structural and molecular insights

A Singh, K Singh, A Sharma, K Kaur… - Chemical Biology & …, 2023 - Wiley Online Library
Fungal infections are posing serious threat to healthcare system due to emerging resistance
among available antifungal agents. Among available antifungal agents in clinical practice …

Medical device-associated healthcare infections: sterilization and the potential of novel biological approaches to ensure patient safety

M Garvey - International Journal of Molecular Sciences, 2023 - mdpi.com
Healthcare-associated infections caused by multi-drug-resistant pathogens are increasing
globally, and current antimicrobial options have limited efficacy against these robust …

Design, synthesis, and activity evaluation of novel dual-target inhibitors with antifungal and immunoregulatory properties

B Sun, W Liu, Q Wang, Y Liu, S Yu… - Journal of Medicinal …, 2023 - ACS Publications
Dual-target (CYP51/PD-L1) plays an important role in the process of fungal proliferation and
immune suppression. A series of novel quinazoline compounds with dual-target inhibition …

Studies on the novel effects of electron beam treated pollen on colony reproductive output in commercially-reared bumblebees (Bombus terrestris) for mass pollination …

J Eakins, M Lynch, JC Carolan, NJ Rowan - Science of the Total …, 2023 - Elsevier
Commercially-reared bumblebees provide an important pollinator service that helps support
food production and security. The deployment of an appropriate non-thermal disinfection …

Phenolic-rich extracts from circular economy: chemical profile and activity against filamentous Fungi and dermatophytes

A Lombardi, M Campo, P Vignolini, M Papalini… - Molecules, 2023 - mdpi.com
Fungal infections represent a relevant issue in agri-food and biomedical fields because they
could compromise quality of food and humans' health. Natural extracts represent a safe …

Use of real-time immersive digital training and educational technologies to improve patient safety during the processing of reusable medical devices: Quo Vadis?

T Kremer, N Murray, J Buckley, NJ Rowan - Science of The Total …, 2023 - Elsevier
Hospital acquired infections stemming from contaminated reusable medical devices are of
increasing concern. This issue is exaggerated with the introduction of complex medical …

A proposed cleaning classification system for reusable medical devices to complement the Spaulding classification

T Kremer, NJ Rowan, G McDonnell - Journal of Hospital Infection, 2023 - Elsevier
A central tenet in infection prevention is the application of the Spaulding classification
system for the safe use of medical devices. Initially defined in the 1950's, this system defines …

Exploring Non-Thermal Plasma and UV Radiation as Biofilm Control Strategies against Foodborne Filamentous Fungal Contaminants

M Kulišová, M Rabochová, J Lorinčík, T Brányik… - Foods, 2024 - mdpi.com
In recent years, non-thermal plasma (NTP) has emerged as a promising tool for
decontamination and disinfection within the food industry. Given the increasing resistance of …

[HTML][HTML] Nano-Selenium inhibited antibiotic resistance genes and virulence factors by suppressing bacterial selenocompound metabolism and chemotaxis pathways …

H Zhang, Z Zhao, W Guan, Y Zhong, Y Wang… - Ecotoxicology and …, 2023 - Elsevier
Numerous antibiotic resistance genes (ARGs) and virulence factors (VFs) found in animal
manure pose significant risks to human health. However, the effects of graphene sodium …

Anticandidal activity and mechanism of action of several cationic chimeric antimicrobial peptides

M Memariani, H Memariani, H Moravvej… - International Journal of …, 2023 - Springer
Antimicrobial peptides (AMPs) have recently been the subject of extensive research in both
academia and commercial sectors because of their rapid, broad-spectrum microbicidal …