Recent advances in antifungal drug development targeting lanosterol 14α‐demethylase (CYP51): a comprehensive review with structural and molecular insights
Fungal infections are posing serious threat to healthcare system due to emerging resistance
among available antifungal agents. Among available antifungal agents in clinical practice …
among available antifungal agents. Among available antifungal agents in clinical practice …
Medical device-associated healthcare infections: sterilization and the potential of novel biological approaches to ensure patient safety
M Garvey - International Journal of Molecular Sciences, 2023 - mdpi.com
Healthcare-associated infections caused by multi-drug-resistant pathogens are increasing
globally, and current antimicrobial options have limited efficacy against these robust …
globally, and current antimicrobial options have limited efficacy against these robust …
Design, synthesis, and activity evaluation of novel dual-target inhibitors with antifungal and immunoregulatory properties
B Sun, W Liu, Q Wang, Y Liu, S Yu… - Journal of Medicinal …, 2023 - ACS Publications
Dual-target (CYP51/PD-L1) plays an important role in the process of fungal proliferation and
immune suppression. A series of novel quinazoline compounds with dual-target inhibition …
immune suppression. A series of novel quinazoline compounds with dual-target inhibition …
Studies on the novel effects of electron beam treated pollen on colony reproductive output in commercially-reared bumblebees (Bombus terrestris) for mass pollination …
J Eakins, M Lynch, JC Carolan, NJ Rowan - Science of the Total …, 2023 - Elsevier
Commercially-reared bumblebees provide an important pollinator service that helps support
food production and security. The deployment of an appropriate non-thermal disinfection …
food production and security. The deployment of an appropriate non-thermal disinfection …
Phenolic-rich extracts from circular economy: chemical profile and activity against filamentous Fungi and dermatophytes
A Lombardi, M Campo, P Vignolini, M Papalini… - Molecules, 2023 - mdpi.com
Fungal infections represent a relevant issue in agri-food and biomedical fields because they
could compromise quality of food and humans' health. Natural extracts represent a safe …
could compromise quality of food and humans' health. Natural extracts represent a safe …
Use of real-time immersive digital training and educational technologies to improve patient safety during the processing of reusable medical devices: Quo Vadis?
Hospital acquired infections stemming from contaminated reusable medical devices are of
increasing concern. This issue is exaggerated with the introduction of complex medical …
increasing concern. This issue is exaggerated with the introduction of complex medical …
A proposed cleaning classification system for reusable medical devices to complement the Spaulding classification
T Kremer, NJ Rowan, G McDonnell - Journal of Hospital Infection, 2023 - Elsevier
A central tenet in infection prevention is the application of the Spaulding classification
system for the safe use of medical devices. Initially defined in the 1950's, this system defines …
system for the safe use of medical devices. Initially defined in the 1950's, this system defines …
Exploring Non-Thermal Plasma and UV Radiation as Biofilm Control Strategies against Foodborne Filamentous Fungal Contaminants
M Kulišová, M Rabochová, J Lorinčík, T Brányik… - Foods, 2024 - mdpi.com
In recent years, non-thermal plasma (NTP) has emerged as a promising tool for
decontamination and disinfection within the food industry. Given the increasing resistance of …
decontamination and disinfection within the food industry. Given the increasing resistance of …
[HTML][HTML] Nano-Selenium inhibited antibiotic resistance genes and virulence factors by suppressing bacterial selenocompound metabolism and chemotaxis pathways …
H Zhang, Z Zhao, W Guan, Y Zhong, Y Wang… - Ecotoxicology and …, 2023 - Elsevier
Numerous antibiotic resistance genes (ARGs) and virulence factors (VFs) found in animal
manure pose significant risks to human health. However, the effects of graphene sodium …
manure pose significant risks to human health. However, the effects of graphene sodium …
Anticandidal activity and mechanism of action of several cationic chimeric antimicrobial peptides
M Memariani, H Memariani, H Moravvej… - International Journal of …, 2023 - Springer
Antimicrobial peptides (AMPs) have recently been the subject of extensive research in both
academia and commercial sectors because of their rapid, broad-spectrum microbicidal …
academia and commercial sectors because of their rapid, broad-spectrum microbicidal …