[HTML][HTML] Hydrogel degradation promotes angiogenic and regenerative potential of cell spheroids for wound healing

VL Thai, DH Ramos-Rodriguez, M Mesfin, JK Leach - Materials Today Bio, 2023 - Elsevier
Chronic nonhealing wounds are debilitating and diminish one's quality of life, necessitating
the development of improved strategies for effective treatment. Biomaterial-and cell-based …

Mesenchymal Stem Cell Spheroids: A Promising Tool for Vascularized Tissue Regeneration

Y Kang, J Na, G Karima, S Amirthalingam… - Tissue Engineering and …, 2024 - Springer
Abstract Background Mesenchymal stem cells (MSCs) are undifferentiated cells that can
differentiate into specific cell lineages when exposed to the right conditions. The ability of …

[HTML][HTML] Mechanoregulation of MSC spheroid immunomodulation

VL Thai, S Mierswa, KH Griffin, JD Boerckel… - APL …, 2024 - pubs.aip.org
Mesenchymal stromal cells (MSCs) are widely used in cell-based therapies and tissue
regeneration for their potent secretome, which promotes host cell recruitment and modulates …

Precision Culture Scaling to Establish High‐Throughput Vasculogenesis Models

NR Dennison, M Fusenig, L Grönnert… - Advanced …, 2024 - Wiley Online Library
Hydrogel‐based 3D cell cultures can recapitulate (patho) physiological phenomena ex vivo.
However, due to their complex multifactorial regulation, adapting these tissue and disease …