Systemic sclerosis-associated interstitial lung disease

A Perelas, RM Silver, AV Arrossi… - The Lancet respiratory …, 2020 - thelancet.com
Systemic sclerosis is an autoimmune connective tissue disease, which is characterised by
immune dysregulation and progressive fibrosis that typically affects the skin, with variable …

Predictors of progression in systemic sclerosis patients with interstitial lung disease

O Distler, S Assassi, V Cottin, M Cutolo… - European …, 2020 - Eur Respiratory Soc
Systemic sclerosis (SSc) is a systemic autoimmune disease affecting multiple organ
systems, including the lungs. Interstitial lung disease (ILD) is the leading cause of death in …

The identification and management of interstitial lung disease in systemic sclerosis: evidence-based European consensus statements

AM Hoffmann-Vold, TM Maher, EE Philpot… - The Lancet …, 2020 - thelancet.com
Background Systemic sclerosis-associated interstitial lung disease (ILD) carries a high
mortality risk; expert guidance is required to aid early recognition and treatment. We aimed …

The natural history of progressive fibrosing interstitial lung diseases

M Kolb, M Vašáková - Respiratory research, 2019 - Springer
A proportion of patients with certain types of interstitial lung disease (ILD), including chronic
hypersensitivity pneumonitis and ILDs associated with autoimmune diseases, develop a …

Etiology, risk factors, and biomarkers in systemic sclerosis with interstitial lung disease

D Khanna, DP Tashkin, CP Denton… - American journal of …, 2020 - atsjournals.org
Systemic sclerosis (SSc) is a complex, multiorgan, autoimmune disease. Lung fibrosis
occurs in∼ 80% of patients with SSc; 25% to 30% develop progressive interstitial lung …

Tracking impact of interstitial lung disease in systemic sclerosis in a complete nationwide cohort

AM Hoffmann-Vold, H Fretheim, AK Halse… - American journal of …, 2019 - atsjournals.org
Rationale: Interstitial lung disease (ILD) represents a major challenge in systemic sclerosis
(SSc), but there are no precise, population-based data on its overall impact, limiting …

2020 guide for the diagnosis and treatment of interstitial lung disease associated with connective tissue disease

Y Kondoh, S Makino, T Ogura, T Suda, H Tomioka… - Respiratory …, 2021 - Elsevier
The prognosis of patients with connective tissue disease (CTD) has improved significantly in
recent years, but interstitial lung disease (ILD) associated with connective tissue disease …

Disparate interferon signaling and shared aberrant basaloid cells in single-cell profiling of idiopathic pulmonary fibrosis and systemic sclerosis-associated interstitial …

E Valenzi, T Tabib, A Papazoglou, J Sembrat… - Frontiers in …, 2021 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) and systemic sclerosis-associated interstitial lung
disease (SSc-ILD) differ in the predominant demographics and identified genetic risk alleles …

Computed tomography-based radiomics decodes prognostic and molecular differences in interstitial lung disease related to systemic sclerosis

J Schniering, M Maciukiewicz… - European respiratory …, 2022 - Eur Respiratory Soc
Background Radiomic features calculated from routine medical images show great potential
for personalised medicine in cancer. Patients with systemic sclerosis (SSc), a rare …

Connective tissue disease-related interstitial lung disease: prevalence, patterns, predictors, prognosis, and treatment

N Jeganathan, M Sathananthan - Lung, 2020 - Springer
Interstitial lung disease is a common pulmonary manifestation of connective tissue diseases
and results in significant morbidity and mortality. Although all connective tissue diseases are …