Coating the surface of nanoparticles with polyethylene glycol (PEG), or “PEGylation”, is a
commonly used approach for improving the efficiency of drug and gene delivery to target …

Polyethylene glycol (PEG) conjugation is a rapidly evolving strategy to solve hurdles in
therapeutic delivery and is being used as an add-on tool to the traditional drug delivery …

Polyethylene glycol (PEG) is a flexible, hydrophilic simple polymer that is physically attached
to peptides, proteins, nucleic acids, liposomes, and nanoparticles to reduce renal clearance …

The early and massive vaccination campaign in Israel with the mRNA-LNP
Comirnaty®(Pfizer-BioNTech) vaccine against the SARS-CoV-2 virus made available large …

Nanomedicines and macromolecular drugs can induce hypersensitivity reactions (HSRs)
with symptoms ranging from flushing and breathing difficulties to hypothermia, hypotension …

Poly (ethylene glycol)(PEG) is the gold standard used to reduce unspecific protein
adsorption and prolong nanocarrier circulation time. However, this stealth effect could be …

Dementia, including Alzheimer's disease (AD), is a major disorder causing visual problems
in the elderly population. The pathology of AD includes the deposition in the brain of …

Injectable drug nanocarriers have greatly benefited in their clinical development from the
addition of a superficial hydrophilic corona to improve their cargo pharmacokinetics. The …

The field of drug delivery is fast expanding and its potentials have already been proved by
the many products in the market. Among all approaches, polymer conjugation is a well …

Two messenger RNA (mRNA)-based vaccines are widely used globally to prevent
coronavirus disease 2019 (COVID-19). Both vaccine formulations contain PEGylated lipids …