Microglia-astrocyte crosstalk has recently been at the forefront of glial research. Emerging
evidence illustrates that microglia-and astrocyte-derived signals are the functional …

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating chronic
disease of unknown aetiology that is recognized by the World Health Organization (WHO) …

Cathepsin B (CTSB) is a powerful lysosomal protease. This review evaluated CTSB gene
knockout (KO) outcomes for amelioration of brain dysfunctions in neurologic diseases and …

Histamine, acting via distinct histamine H1, H2, H3, and H4 receptors, regulates various
physiological and pathological processes, including pain. In the last two decades, there has …

Background Recent evidence has suggested that peripheral inflammatory responses
induced by lipopolysaccharides (LPS) play an important role in neuropsychiatric dysfunction …

Microglia are the principal resident immune cells in the central nervous system and are
believed to be versatile players in both inflammatory and physiological contexts. On the one …

Spinal cord stimulation (SCS) as an evidence‐based interventional treatment has been
used and approved for clinical use in a variety of pathological states including peripheral …

Background Dry eye disease (DED) is a multifactorial disease associated with ocular
surface inflammation, pain, and nerve abnormalities. We studied the peripheral and central …

This narrative review examines the possible role of microglial cells, first, in
neuroinflammation and, second, in schizophrenia, depression, and suicide. Recent research …

Objective This study was undertaken to identify susceptibility loci for cluster headache and
obtain insights into relevant disease pathways. Methods We carried out a genome‐wide …