[HTML][HTML] An immunophenotype-coupled transcriptomic atlas of human hematopoietic progenitors
Abstract Analysis of the human hematopoietic progenitor compartment is being transformed
by single-cell multimodal approaches. Cellular indexing of transcriptomes and epitopes by …
by single-cell multimodal approaches. Cellular indexing of transcriptomes and epitopes by …
The role of immune reconstitution in relapse after allogeneic hematopoietic stem cell transplantation
XY Pei, XJ Huang - Expert Review of Clinical Immunology, 2024 - Taylor & Francis
Introduction Leukemia relapse following stem cell transplantation remains a significant
barrier to long-term remission. Timely and balanced immune recovery after transplantation is …
barrier to long-term remission. Timely and balanced immune recovery after transplantation is …
[HTML][HTML] Cross-species transcriptomics reveals bifurcation point during the arterial-to-hemogenic transition
S Mo, K Qu, J Huang, Q Li, W Zhang, K Yen - Communications Biology, 2023 - nature.com
Hemogenic endothelium (HE) with hematopoietic stem cell (HSC)-forming potential emerge
from specialized arterial endothelial cells (AECs) undergoing the endothelial-to …
from specialized arterial endothelial cells (AECs) undergoing the endothelial-to …
Safety of romiplostim administered immediately after cord-blood transplantation: a phase 1 trial
Graft failure and delayed hematopoietic recovery are the major limitations of cord-blood
transplantation (CBT). Romiplostim, a thrombopoietin-receptor agonist, promotes …
transplantation (CBT). Romiplostim, a thrombopoietin-receptor agonist, promotes …
[HTML][HTML] Single-cell genomics-based immune and disease monitoring in blood malignancies
Achieving long-term disease control using therapeutic immunomodulation is a long-standing
concept with a strong tradition in blood malignancies. Besides allogeneic hematopoietic …
concept with a strong tradition in blood malignancies. Besides allogeneic hematopoietic …
[HTML][HTML] Monocytes in allo-HSCT with aged donors secrete IL-1/IL-6/TNF to increase the risk of GVHD and damage the aged HSCs
X Li, W Zhang, Y Wang, C Li, Y Wu, Y Shang, H Lin… - Iscience, 2024 - cell.com
Aging is considered a critical factor of poor prognosis in allogenic hemopoietic stem cell
transplantation (allo-HSCT). To elucidate the underlying mechanisms, we comprehensively …
transplantation (allo-HSCT). To elucidate the underlying mechanisms, we comprehensively …
[PDF][PDF] Biological Properties of Hematopoietic Stem Cells: Scientific Basis for Hematopoietic Cell Transplantation
Hematopoiesis—from the Greek term for “blood making”—is the adaptive process by which
mature and functional blood cells are continuously replaced over the entire lifetime of an …
mature and functional blood cells are continuously replaced over the entire lifetime of an …
[HTML][HTML] Charting epimutation dynamics in human hematopoietic differentiation
X Qin, J Lu, P Wu, C Zhang, L Shi, P Zhu - Blood Science, 2024 - journals.lww.com
DNA methylation plays a critical role in hematopoietic differentiation. Epimutation is a
stochastic variation in DNA methylation that induces epigenetic heterogeneity. However, the …
stochastic variation in DNA methylation that induces epigenetic heterogeneity. However, the …
Towards a blood ecosystem approach to dissect systemic diseases
H Wang, T Cheng - Science China. Life sciences, 2024 - pubmed.ncbi.nlm.nih.gov
Towards a blood ecosystem approach to dissect systemic diseases Towards a blood ecosystem
approach to dissect systemic diseases Sci China Life Sci. 2024 Mar 5. doi …
approach to dissect systemic diseases Sci China Life Sci. 2024 Mar 5. doi …
[HTML][HTML] China's top 10 achievements in hematology in 2023
S Liu, B Chen - Blood Science, 2024 - journals.lww.com
At the 4 th Annual Meeting of the Chinese Alliance for Societies of Hematology (CASH) on
January 7, 2024, the “China's Top 10 achievements in hematology in 2023” were unveiled …
January 7, 2024, the “China's Top 10 achievements in hematology in 2023” were unveiled …