The role of cancer-associated fibroblasts and fibrosis in liver cancer
S Affo, LX Yu, RF Schwabe - Annual Review of Pathology …, 2017 - annualreviews.org
Liver cancer is the second leading cause of cancer mortality worldwide, causing more than
700,000 deaths annually. Because of the wide landscape of genomic alterations and limited …
700,000 deaths annually. Because of the wide landscape of genomic alterations and limited …
[HTML][HTML] The angiopoietin/Tie2 pathway in hepatocellular carcinoma
B Vanderborght, S Lefere, HV Vlierberghe… - Cells, 2020 - mdpi.com
Due to the usually late diagnosis and lack of effective therapies, hepatocellular carcinoma
(HCC), which poses a growing global health problem, is characterized by a poor prognosis …
(HCC), which poses a growing global health problem, is characterized by a poor prognosis …
Ceramide metabolism regulates autophagy and apoptotic cell death induced by melatonin in liver cancer cells
R Ordoñez, A Fernández… - Journal of pineal …, 2015 - Wiley Online Library
Autophagy is a process that maintains homeostasis during stress, although it also
contributes to cell death under specific contexts. Ceramides have emerged as important …
contributes to cell death under specific contexts. Ceramides have emerged as important …
Fluorescence lifetime needle optical biopsy discriminates hepatocellular carcinoma
EA Zherebtsov, EV Potapova, AV Mamoshin… - Biomedical Optics …, 2022 - opg.optica.org
This work presents results of in vivo and in situ measurements of hepatocellular carcinoma
by a developed optical biopsy system. Here, we describe the technical details of the …
by a developed optical biopsy system. Here, we describe the technical details of the …
Chronic cadmium exposure at environmental-relevant level accelerates the development of hepatotoxicity to hepatocarcinogenesis
Y Xu, W Mu, J Li, Q Ba, H Wang - Science of the Total Environment, 2021 - Elsevier
Cadmium (Cd) is an environmental heavy metal with long biological half-time and adverse
health effects. The long-term toxicity of Cd at low levels remains to be elucidated. Here, we …
health effects. The long-term toxicity of Cd at low levels remains to be elucidated. Here, we …
[HTML][HTML] Machine learning identifies ferroptosis-related gene ANXA2 as potential diagnostic biomarkers for NAFLD
J Qin, P Cao, X Ding, Z Zeng, L Deng… - Frontiers in …, 2023 - frontiersin.org
Introduction Non-alcoholic fatty liver disease (NAFLD), a major cause of chronic liver
disease, still lacks effective therapeutic targets today. Ferroptosis, a type of cell death …
disease, still lacks effective therapeutic targets today. Ferroptosis, a type of cell death …
Harmine induces apoptosis in HepG2 cells via mitochondrial signaling pathway
Background Harmine has antitumor and antinociceptive effects, and inhibits human DNA
topoisomerase. However, no detailed data are available on the mechanisms of action of …
topoisomerase. However, no detailed data are available on the mechanisms of action of …
A Huaier polysaccharide restrains hepatocellular carcinoma growth and metastasis by suppression angiogenesis
C Li, X Wu, H Zhang, G Yang, M Hao, S Sheng… - International journal of …, 2015 - Elsevier
Hepatocellular carcinoma (HCC) is a highly metastatic cancer. Huaier polysaccharide (TP-1)
is a naturally occurring bioactive macromolecule, found in Huaier fungus and has been …
is a naturally occurring bioactive macromolecule, found in Huaier fungus and has been …
Targeting molecular signal transduction pathways in hepatocellular carcinoma and its implications for cancer therapy
IH Mir, S Guha, J Behera… - Cell Biology …, 2021 - Wiley Online Library
Hepatocellular carcinoma is a substantial health concern. It is currently the third dominating
cause of mortality associated with cancer worldwide. The development of hepatocellular …
cause of mortality associated with cancer worldwide. The development of hepatocellular …
[HTML][HTML] Expression of microRNA-150 targeting vascular endothelial growth factor-A is downregulated under hypoxia during liver regeneration
ZY Yu, YN Bai, LX Luo, H Wu… - Molecular Medicine …, 2013 - spandidos-publications.com
Vascular endothelial growth factor (VEGF) is a factor that stimulates the proliferation of
sinusoidal endothelial cells and hepatocytes during liver regeneration (LR). The present …
sinusoidal endothelial cells and hepatocytes during liver regeneration (LR). The present …