[HTML][HTML] Clinical outcome, incidence, and SARS-CoV-2 infection-fatality rates in Italian patients with inborn errors of immunity

C Milito, V Lougaris, G Giardino… - The Journal of …, 2021 - jaci-inpractice.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-positive patients with
inborn errors of immunity (IEI) showed a similar infection-fatality rate, a lower incidence in …

[HTML][HTML] Harnessing type I IFN immunity against SARS-CoV-2 with early administration of IFN-β

DC Vinh, L Abel, P Bastard, MP Cheng… - Journal of clinical …, 2021 - Springer
Since December 2019, over 150 million individuals have been infected with SARS-CoV-2
globally. While most cases (> 95%) are asymptomatic or mild, a small proportion develop …

Anti‐IFN‐α/‐ω neutralizing antibodies from COVID‐19 patients correlate with downregulation of IFN response and laboratory biomarkers of disease severity

F Frasca, M Scordio, L Santinelli… - European journal of …, 2022 - Wiley Online Library
A significant number of COVID‐19 patients were shown to have neutralizing antibodies
(NAB) against IFN; however, NAB specificity, fluctuation over time, associations with …

[HTML][HTML] COVID-19 in the context of inborn errors of immunity: a case series of 31 patients from Mexico

LM Castano-Jaramillo… - Journal of clinical …, 2021 - Springer
Introduction Patients with inborn errors of immunity (IEI) have a compromised or
inappropriate immune response. Although they might be considered a high-risk group for …

[HTML][HTML] The immune response to SARS-CoV-2 vaccination: insights learned from adult patients with common variable immune deficiency

I Quinti, F Locatelli, R Carsetti - Frontiers in Immunology, 2022 - frontiersin.org
CVID patients have an increased susceptibility to vaccine-preventable infections. The
question on the potential benefits of immunization of CVID patients against SARS-CoV-2 …

COVID-19 and inborn errors of immunity

OM Delmonte, R Castagnoli, LD Notarangelo - Physiology, 2022 - journals.physiology.org
Inborn errors of immunity (IEI) are a heterogeneous group of disorders affecting immune
host defense and immunoregulation. Considering the predisposition to develop severe and …

Common variable immunodeficiency disorders, T-cell responses to SARS-CoV-2 vaccines, and the risk of chronic COVID-19

R Ameratunga, H Longhurst, R Steele, K Lehnert… - The Journal of Allergy …, 2021 - Elsevier
COVID-19 has had a calamitous effect on the global community. Despite intense study, the
immunologic response to the infection is only partially understood. In addition to older age …

[HTML][HTML] Robust antibody and T cell responses to SARS-CoV-2 in patients with antibody deficiency

H Kinoshita, J Durkee-Shock… - Journal of Clinical …, 2021 - Springer
Immunocompromised patients, including those with inborn errors of immunity (IEI), may be at
increased risk for severe or prolonged infections with SARS-CoV-2 (Zhu et al. N Engl J Med …

Guardians of the oral and nasopharyngeal galaxy: IgA and protection against SARS‐CoV‐2 infection

S Sheikh‐Mohamed, EC Sanders… - Immunological …, 2022 - Wiley Online Library
In early 2020, a global emergency was upon us in the form of the coronavirus disease 2019
(COVID‐19) pandemic. While horrific in its health, social and economic devastation, one …

[HTML][HTML] Production and persistence of specific antibodies in COVID-19 patients with hematologic malignancies: role of rituximab

C Cattaneo, V Cancelli, L Imberti, K Dobbs… - Blood Cancer …, 2021 - nature.com
The ability of patients with hematologic malignancies (HM) to develop an effective humoral
immune response after COVID-19 is unknown. A prospective study was performed to …