Engineered extracellular vesicles and their mimetics for cancer immunotherapy
C Liu, Y Wang, L Li, D He, J Chi, Q Li, Y Wu… - Journal of Controlled …, 2022 - Elsevier
Extracellular vesicles (EVs) are heterogeneous membranous vesicles secreted by living
cells that are involved in many physiological and pathological processes as intermediaries …
cells that are involved in many physiological and pathological processes as intermediaries …
[HTML][HTML] Extracellular vesicles in ovarian cancer chemoresistance, metastasis, and immune evasion
W Tian, N Lei, J Zhou, M Chen, R Guo, B Qin, Y Li… - Cell Death & …, 2022 - nature.com
Chemoresistance and metastasis are the major challenges for the current ovarian cancer
treatment. Understanding the mechanisms of ovarian cancer progression and metastasis is …
treatment. Understanding the mechanisms of ovarian cancer progression and metastasis is …
[HTML][HTML] Scalable production of extracellular vesicles and its therapeutic values: a review
CY Ng, LT Kee, ME Al-Masawa, QH Lee… - International Journal of …, 2022 - mdpi.com
Extracellular vesicles (EVs) are minute vesicles with lipid bilayer membranes. EVs are
secreted by cells for intercellular communication. Recently, EVs have received much …
secreted by cells for intercellular communication. Recently, EVs have received much …
[HTML][HTML] Nanocarriers surface engineered with cell membranes for cancer targeted chemotherapy
W Lei, C Yang, Y Wu, G Ru, X He, X Tong… - Journal of …, 2022 - Springer
Background Inspired by nature, the biomimetic approach has been incorporated into drug
nanocarriers for cancer targeted chemotherapy. The nanocarriers are cloaked in cell …
nanocarriers for cancer targeted chemotherapy. The nanocarriers are cloaked in cell …
Cell-derived biomimetic nanocarriers for targeted cancer therapy: cell membranes and extracellular vesicles
Nanotechnology provides synthetic carriers for cancer drug delivery that protect cargos from
degradation, control drug release and increase local accumulation at tumors. However …
degradation, control drug release and increase local accumulation at tumors. However …
Exosome-based nanomedicine for cancer treatment by targeting inflammatory pathways: current status and future perspectives
MA Ansari, M Thiruvengadam, B Venkidasamy… - Seminars in cancer …, 2022 - Elsevier
Cancer is one of the dreadful diseases worldwide. Surgery, radiation and chemotherapy, are
the three basic standard modes of cancer treatment. However, difficulties in cancer treatment …
the three basic standard modes of cancer treatment. However, difficulties in cancer treatment …
Biomimetic immunomodulation strategies for effective tissue repair and restoration
Inflammation plays a central role in wound healing following injury or disease and is
mediated by a precise cascade of cellular and molecular events. Unresolved inflammatory …
mediated by a precise cascade of cellular and molecular events. Unresolved inflammatory …
Mesenchymal stem cells, exosomes and exosome-mimics as smart drug carriers for targeted cancer therapy
Mesenchymal stem cells (MSCs) are multipotent stem cells with the capacity to differentiate
into several cell types under appropriate conditions. They also possess remarkable …
into several cell types under appropriate conditions. They also possess remarkable …
Immune-cell-derived exosomes for cancer therapy
Exosomes are a type of extracellular vesicles secreted by cells in normal or pathological
conditions for cell–cell communication. With immunomodulatory characteristics and potential …
conditions for cell–cell communication. With immunomodulatory characteristics and potential …
[HTML][HTML] Exosomes derived from 3D-cultured MSCs improve therapeutic effects in periodontitis and experimental colitis and restore the Th17 cell/Treg balance in …
Y Zhang, J Chen, H Fu, S Kuang, F He… - International journal of …, 2021 - nature.com
Although mesenchymal stem cell-derived exosomes (MSC-exos) have been shown to have
therapeutic effects in experimental periodontitis, their drawbacks, such as low yield and …
therapeutic effects in experimental periodontitis, their drawbacks, such as low yield and …