The authors identified individual randomized controlled trials from previous meta-analyses
and additional searches, and then performed meta-analyses on cardiovascular disease …

Hyperhomocysteinemia/Homocysteinuria is characterized by an increased level of toxic
homocysteine in the plasma. The plasma concentration of homocysteine is 5–15 μmol/L in …

Abstract The American Cancer Society (ACS) publishes Nutrition and Physical Activity
Guidelines to serve as a foundation for its communication, policy, and community strategies …

Folate, an essential micronutrient, is a critical cofactor in one-carbon metabolism. Mammals
cannot synthesize folate and depend on supplementation to maintain normal levels. Low …

Alcohol consumption by adult women is consistently associated with risk of breast cancer.
Several questions regarding alcohol and breast cancer need to be addressed. Menarche to …

ContextLaboratory and epidemiological data suggest that folic acid may have an
antineoplastic effect in the large intestine. ObjectiveTo assess the safety and efficacy of folic …

Fortification of food with folic acid to reduce the number of neural tube defects was
introduced 10 y ago in North America. Many countries are considering whether to adopt this …

Context Recently, concern has been raised about the safety of folic acid, particularly in
relation to cancer risk. Objective To evaluate effects of treatment with B vitamins on cancer …

This is an update of the previous 2018 systematic review and meta-analysis of vitamin and
mineral supplementation on cardiovascular disease outcomes and all-cause mortality. New …

The search for a connection between diet and human cancer has a long history in cancer
research, as has interest in the mechanisms by which dietary factors might increase or …