[HTML][HTML] Multilayered regulation of secondary metabolism in medicinal plants

Y Zhao, G Liu, F Yang, Y Liang, Q Gao, C Xiang… - Molecular …, 2023 - Springer
Medicinal plants represent a huge reservoir of secondary metabolites (SMs), substances
with significant pharmaceutical and industrial potential. However, obtaining secondary …

Molecular regulation of the key specialized metabolism pathways in medicinal plants

M Shi, S Zhang, Z Zheng, I Maoz… - Journal of Integrative …, 2024 - Wiley Online Library
The basis of modern pharmacology is the human ability to exploit the production of
specialized metabolites from medical plants, for example, terpenoids, alkaloids, and …

AaABI5 transcription factor mediates light and abscisic acid signaling to promote anti-malarial drug artemisinin biosynthesis in Artemisia annua

Y Li, Y Yang, P Li, M Sheng, L Li, X Ma, Z Du… - International Journal of …, 2023 - Elsevier
Artemisia annua, a member of the Asteraceae family, remains the primary source of
artemisinin. However, the artemisinin content in the existing varieties of this plant is very low …

Transcription factor PgNAC72 activates DAMMARENEDIOL SYNTHASE expression to promote ginseng saponin biosynthesis

T Jiang, Y Zhang, G Zuo, T Luo, H Wang… - Plant …, 2024 - academic.oup.com
Ginsenosides, the primary bioactive constituents in ginseng (Panax ginseng), possess
substantial pharmacological potential and are in high demand in the market. The plant …

Chemoproteomics reveals the epoxidase enzyme for the biosynthesis of camptothecin in Ophiorrhiza pumila

T Zhang, Y Wang, S Wu, E Tian, C Yang… - Journal of Integrative …, 2024 - Wiley Online Library
Camptothecin is one of the most commonly used anticancer drugs worldwide, yet the
downstream biosynthetic route from strictosidine to camptothecin has remained unclear for …

Comprehensive analysis of OpHD-ZIP transcription factors related to the regulation of camptothecin biosynthesis in Ophiorrhiza pumila

J Wang, Y Li, Y Yang, C Xiao, Q Ruan, P Li… - International Journal of …, 2023 - Elsevier
Ophiorrhiza pumila, as a folk herb belonging to the Rubiaceae family, has become a
potential source of camptothecin (CPT), which is a monoterpenoid indole alkaloid with good …

A stress-responsive R2R3-MYB transcription factor, EpMYB1 is involved in the regulation of anthocyanin biosynthesis in purple coneflower

G Jin, Z Deng, H Wang, W Li, L Su, Y Zhang… - Industrial Crops and …, 2024 - Elsevier
Purple coneflower (Echinacea purpurea (L.) Menoch), a North American native and world-
popular medicinal and horticultural plant, has been named after its beautiful purple petals …

[HTML][HTML] Unlocking the genetic potential: Strategies for enhancing secondary metabolite biosynthesis in plants

NM Al Aboud - Journal of the Saudi Society of Agricultural Sciences, 2024 - Elsevier
The majority of secondary metabolites (SMs) are derived from plant defense, and they are
crucial for the research and development of novel drugs. This article is an extensive …

Hairy root culture: a reliable bioreactor from transgenic plants

N Atabaki, NA Shaharuddin, SA Ahmad, R Nulit… - Peptide and protein drug …, 2024 - Elsevier
Plants can produce diverse arrays of specialized metabolites with different biological
activities, which are used as raw materials in cosmetics, flavors, fragrances, pigments, and …

Genome-wide analysis of the ERF Family in Stephania japonica provides insights into the regulatory role in Cepharanthine biosynthesis

H Yang, B Liu, H Ding, Z Liu, X Li, T He, Y Wu… - Frontiers in Plant …, 2024 - frontiersin.org
Introduction Cepharanthine (CEP), a bisbenzylisoquinoline alkaloid (bisBIA) extracted from
Stephania japonica, has received significant attention for its anti-coronavirus properties …