The next therapeutic challenge in HIV: polypharmacy
EJ Edelman, KS Gordon, J Glover, IR McNicholl… - Drugs & aging, 2013 - Springer
With the adoption of combination antiretroviral therapy (ART), most HIV-infected individuals
in care are on five or more medications and at risk of harm from polypharmacy, a risk that …
in care are on five or more medications and at risk of harm from polypharmacy, a risk that …
Health outcomes associated with crack-cocaine use: Systematic review and meta-analyses
Background Crack-cocaine use is prevalent largely in socio-economically marginalized
populations in the Americas. Its use has been associated with diverse health outcomes, yet …
populations in the Americas. Its use has been associated with diverse health outcomes, yet …
Presence of Tat and transactivation response element in spinal fluid despite antiretroviral therapy
Objective: The aim of this study was to measure the protein concentration and biological
activity of HIV-1 Tat in cerebrospinal fluid (CSF) of individuals on suppressive antiretroviral …
activity of HIV-1 Tat in cerebrospinal fluid (CSF) of individuals on suppressive antiretroviral …
Alcohol use accelerates HIV disease progression
The effects of alcohol abuse on HIV disease progression have not been definitively
established. A prospective, 30-month, longitudinal study of 231 HIV+ adults included history …
established. A prospective, 30-month, longitudinal study of 231 HIV+ adults included history …
HIV treatment outcomes among HIV-infected, opioid-dependent patients receiving buprenorphine/naloxone treatment within HIV clinical care settings: results from a …
Background: Having opioid dependence and HIV infection are associated with poor HIV-
related treatment outcomes. Methods: HIV-infected, opioid-dependent subjects (N= 295) …
related treatment outcomes. Methods: HIV-infected, opioid-dependent subjects (N= 295) …
Understanding viral and immune interplay during vertical transmission of HIV: implications for cure
O Amin, J Powers, KM Bricker, A Chahroudi - Frontiers in Immunology, 2021 - frontiersin.org
Despite the significant progress that has been made to eliminate vertical HIV infection, more
than 150,000 children were infected with HIV in 2019, emphasizing the continued need for …
than 150,000 children were infected with HIV in 2019, emphasizing the continued need for …
The effects of psychostimulant drugs on blood brain barrier function and neuroinflammation
SM Kousik, TC Napier, PM Carvey - Frontiers in pharmacology, 2012 - frontiersin.org
The blood brain barrier (BBB) is a highly dynamic interface between the central nervous
system (CNS) and periphery. The BBB is comprised of a number of components and is part …
system (CNS) and periphery. The BBB is comprised of a number of components and is part …
Substance use: impact on adherence and HIV medical treatment
A Gonzalez, J Barinas, C O'Cleirigh - Current HIV/AIDS Reports, 2011 - Springer
Substance use is highly prevalent among people living with HIV/AIDS, is often comorbid with
other mental health problems, related to poor HIV medical outcomes, and, is associated with …
other mental health problems, related to poor HIV medical outcomes, and, is associated with …
Alcohol and substance use among transgender women in S an F rancisco: Prevalence and association with human immunodeficiency virus infection
Abstract Introduction and Aims Alcohol and substance use can have negative health
consequences among both human immunodeficiency virus (HIV)‐positive and‐negative …
consequences among both human immunodeficiency virus (HIV)‐positive and‐negative …
Alcohol and HIV disease progression: weighing the evidence
Heavy alcohol use is commonplace among HIV-infected individuals; however, the extent
that alcohol use adversely impacts HIV disease progression has not been fully elucidated …
that alcohol use adversely impacts HIV disease progression has not been fully elucidated …