Exploring the therapeutic potential of targeting GH and IGF-1 in the management of obesity: Insights from the interplay between these hormones and metabolism
S Al-Samerria, S Radovick - International journal of molecular sciences, 2023 - mdpi.com
Obesity is a growing public health problem worldwide, and GH and IGF-1 have been studied
as potential therapeutic targets for managing this condition. This review article aims to …
as potential therapeutic targets for managing this condition. This review article aims to …
Growth hormone treatment for non-GHD disorders: Excitement tempered by biology
A Grimberg, CP Hawkes - The Journal of Clinical Endocrinology …, 2024 - academic.oup.com
The success of growth hormone (GH) replacement in children with classical GH deficiency
has led to excitement that other causes of short stature may benefit similarly. However …
has led to excitement that other causes of short stature may benefit similarly. However …
Fasting and prolonged food restriction differentially affect GH secretion independently of GH receptor signaling in AgRP neurons
ME de Sousa, DO Gusmao… - Journal of …, 2023 - Wiley Online Library
Growth hormone (GH) receptor (GHR) is abundantly expressed in neurons that co‐release
the agouti‐related protein (AgRP) and neuropeptide Y (NPY) in the arcuate nucleus of the …
the agouti‐related protein (AgRP) and neuropeptide Y (NPY) in the arcuate nucleus of the …
Central growth hormone action regulates neuroglial and proinflammatory markers in the hypothalamus of male mice
Growth hormone (GH) action in specific neuronal populations regulates neuroendocrine
responses, metabolism, and behavior. However, the potential role of central GH action on …
responses, metabolism, and behavior. However, the potential role of central GH action on …
The Pattern of GH Action in the Mouse Brain
F Menezes, F Wasinski, GO de Souza, AP Nunes… - …, 2024 - academic.oup.com
Growth hormone (GH) acts in numerous organs expressing the GH receptor (GHR),
including the brain. However, the mechanisms behind the brain's permeability to GH and …
including the brain. However, the mechanisms behind the brain's permeability to GH and …
[HTML][HTML] Local cannabinoid receptor type-1 regulates glial cell activity and insulin-like growth factor-1 receptor signaling in the mediobasal hypothalamus
M Palmisano, CF Ramunno, E Farhat… - Mechanisms of Ageing …, 2024 - Elsevier
As organisms age, the activity of the endocannabinoid system in the brain declines,
coinciding with increased neuroinflammation and disrupted hypothalamic functions. Notably …
coinciding with increased neuroinflammation and disrupted hypothalamic functions. Notably …
Effects of growth hormone therapy on the onset and progression of pubertal development in girls with idiopathic short stature
F Zhu, Q Xu, L Huang, J Zhu, L Huang… - Gynecological …, 2024 - Taylor & Francis
Objective The aim of this study was to explore the impact of growth hormone (GH) therapy
on the onset and progression of puberty in girls with idiopathic short stature. Methods This …
on the onset and progression of puberty in girls with idiopathic short stature. Methods This …
[PDF][PDF] Growth hormone treatment for non-GHD disorders: Excitement
A Grimberg, CP Hawkes - 2023 - cora.ucc.ie
The success of growth hormone (GH) replacement in children with classical GH deficiency
has led to excitement that other causes of short stature may benefit similarly. However …
has led to excitement that other causes of short stature may benefit similarly. However …