Asthma and allergy are common conditions with complex etiologies involving both genetic
and environmental contributions. Recent genome‐wide association studies (GWAS) and …

The vast majority of patients with asthma have rhinitis, and rhinitis is a major independent
risk factor for asthma in cross-sectional and longitudinal studies. The relationships between …

Background: Children with allergic rhinitis are likely to develop asthma. Objective: The
purpose of this investigation was to determine whether specific immunotherapy can prevent …

The International Union against Tuberculosis and Lung Disease (IUATLD) Bronchial
Symptoms Questionnaire (1984) was developed for use in studies of asthma and its …

Dysfunction of the upper and lower airways frequently coexist, and they appear to share key
elements of pathogenesis. Data from epidemiologic studies indicate that nasal symptoms …

Allergic rhinitis and asthma are linked by epidemiologic, histologic, physiologic, and
immunopathologic characteristics and by a common therapeutic approach …

The effect of treatment of allergic rhinitis with intranasal corticosteroids on lower airway
responsiveness was assessed in a randomized, double-blind, placebo-controlled, crossover …

Rhinitis and asthma are often associated and the two disorders interact at various levels.
Rhinitis typically precedes the development of asthma and can contribute to unsatisfactory …

Airway hyperresponsiveness (AHR) and airway inflammation are key pathophysiological
features of asthma. Bronchial provocation tests (BPTs) are objective tests for AHR that are …

In order to study whether the methacholine inhalation challenge could predict which patients
with allergic rhinitis were at risk to develop asthma, we prospectively studied a group of …